1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Desmethyl Erlotinib

Desmethyl Erlotinib (Synonyms: OSI-420 free base; CP-373420)

目录号: HY-13256A
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Desmethyl Erlotinib (OSI-420 free base) 是 Erlotinib 的活性代谢物,Erlotinib 为 EGFR 酪氨酸激酶抑制剂。

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Desmethyl Erlotinib Chemical Structure

Desmethyl Erlotinib Chemical Structure

CAS No. : 183321-86-0

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Description

Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor[1].

In Vivo

Desmethyl Erlotinib exhibits t1/2 of 11.96±2.01 h in a pharmacokinetic study in Wistar rats[1].

Molecular Weight

379.41

Formula

C₂₁H₂₁N₃O₄

CAS No.

183321-86-0

SMILES

OCCOC1=CC2=C(N=CN=C2NC3=CC=CC(C#C)=C3)C=C1OCCOC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Desmethyl ErlotinibOSI-420CP-373420OSI420OSI 420CP373420CP 373420Drug MetaboliteInhibitorinhibitorinhibit

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产品名称:
Desmethyl Erlotinib
目录号:
HY-13256A
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