1. Others Immunology/Inflammation
  2. Isotope-Labeled Compounds COX
  3. Diflunisal-d3

Diflunisal-d3  (Synonyms: 二氟尼柳-d3; MK-647-d3)

目录号: HY-18342S
产品使用指南

Diflunisal-d3 是 Diflunisal 的氘代物。Diflunisal (MK-647) 是一种水杨酸盐衍生物,具有非甾体抗炎和尿酸舒缓性能,可单独用作止痛剂和类风湿关节炎患者。Diflunisal是环氧合酶 (COX) 的抑制剂。

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Diflunisal-d<sub>3</sub> Chemical Structure

Diflunisal-d3 Chemical Structure

CAS No. : 1286107-99-0

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生物活性

Diflunisal-d3 is the deuterium labeled Diflunisal. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

253.22

Formula

C13H5D3F2O3

CAS 号
中文名称

二氟尼柳-d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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