Metastatic Melanoma  (转移性黑色素瘤)

转移性黑色素瘤是一种进展性皮肤癌，恶性细胞从原发肿瘤脱落，经血液或淋巴系统播散，并在远处形成继发性肿瘤。尽管肿瘤细胞最初从原发病灶脱落的效率很高，但随后形成存活转移灶的情况却极为罕见，大约每108个播散细胞中仅有1个能够成功播散并形成新的肿瘤，这凸显了尽管细胞播散广泛，但转移启动的效率却很低。

Metastatic melanoma is a progressive form of skin cancer where malignant cells detach from the primary tumor, disseminate via blood or lymphatic systems, and establish secondary tumors at distant sites. Although the initial detachment of tumor cells from the primary lesion is highly efficient, the subsequent establishment of viable metastases is extremely rare, with only approximately one in 108 disseminated cells successfully seeding and forming new tumors, highlighting the inefficiency of metastasis initiation despite widespread cell dissemination.

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