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  4. Docosahexaenoyl Serinol

Docosahexaenoyl Serinol (Compound 1) 抑制肺癌细胞 A549 增殖，在 3 μM 时抑制率为 77.4%。

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Docosahexaenoyl Serinol

Docosahexaenoyl Serinol Chemical Structure

CAS No. : 1638355-62-0

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规格 价格 是否有货 数量
1 mg (12.45 mM * 200 μL in Ethanol) ￥864
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Docosahexaenoyl Serinol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Docosahexaenoyl Serinol (Compound 1) inhibits proliferation of lung cancaer cells A549, with 77.4% inhibition rate at 3 μM[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
0.48 μM
Compound: 1
Growth inhibition of human A549 cells after 48 hrs by trypan blue dye exclusion method
Growth inhibition of human A549 cells after 48 hrs by trypan blue dye exclusion method
[PMID: 25466189]
RBL-2H3 IC50
16 μM
Compound: 28
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside substrate based assay
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside substrate based assay
[PMID: 31618024]
Sf9 IC50
> 50 μM
Compound: 28
Inhibition of human FAAH expressed in baculovirus infected Sf9 cells using N-(6-methoxypyridin-3-yl)octanamide as substrate measured for 15 mins by fluorescence based assay
Inhibition of human FAAH expressed in baculovirus infected Sf9 cells using N-(6-methoxypyridin-3-yl)octanamide as substrate measured for 15 mins by fluorescence based assay
[PMID: 31618024]
分子量

401.58

Formula

C25H39NO3
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Solution, -20°C, 2 years
纯度 & 产品资料

纯度: 99.0%

COA (275 KB)

产品使用指南 (1538 KB)
参考文献

Docosahexaenoyl Serinol 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Docosahexaenoyl Serinol1638355-62-0Drug DerivativeDrug derivativeLung cancerA549Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-160927
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