2. Anti-infection
  3. Bacterial
  4. DprE1-IN-7

DprE1-IN-7 (Compound 64) 是一种 DprE1 抑制剂。DprE1-IN-7 对 Mtb H37Rv 菌株具有抗结核活性 (MIC: 4 μM)。DprE1-IN-7 还具有针对耐药菌株的抗分枝杆菌活性。DprE1-IN-7 具有较高的微粒体稳定性中等清除速率。

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DprE1-IN-7

DprE1-IN-7 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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DprE1-IN-7 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DprE1-IN-7 (Compound 64) is a DprE1 inhibitor. DprE1-IN-7 has anti-TB activity against Mtb H37Rv strain (MIC: 1 μM). DprE1-IN-7 also has antimycobacterial activity against drug-resistant strains. DprE1-IN-7 has high microsomal stability and medium clearance[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
H9c2 IC50
> 50 μM
Compound: 64
Cytotoxicity against rat H9c2 cells assessed as cell viability incubated for 72 hrs by MTT spectrophotometric analysis
Cytotoxicity against rat H9c2 cells assessed as cell viability incubated for 72 hrs by MTT spectrophotometric analysis
[PMID: 37421887]
HepG2 IC50
> 125 μM
Compound: 64
Cytotoxicity against human HepG2 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human HepG2 cells incubated for 24 hrs by MTT assay
[PMID: 37421887]
HepG2 IC50
> 50 μM
Compound: 64
Cytotoxicity against human HepG2 cells assessed as cell viability incubated for 72 hrs by MTT spectrophotometric analysis
Cytotoxicity against human HepG2 cells assessed as cell viability incubated for 72 hrs by MTT spectrophotometric analysis
[PMID: 37421887]
分子量

360.41

Formula

C20H20N6O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DprE1-IN-7 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DprE1-IN-7BacterialMtbH37Rvanti-TBantimycobacterialInhibitorinhibitorinhibit

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目录号：
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