2. Gene
  3. Pawr - PRKC, apoptosis, WT1, regulator Gene

Pawr - PRKC, apoptosis, WT1, regulator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PAR4; Par-4; 2310001G03Rik

基因 ID: 114774 | 基因类型: protein coding

关于 Pawr

功能概要

Predicted to enable actin binding activity; enzyme binding activity; and leucine zipper domain binding activity. Involved in negative regulation of fibroblast proliferation; regulation of cellular response to stress; and regulation of gene expression. Acts upstream of or within several processes, including negative regulation of T cell receptor signaling pathway; negative regulation of lymphocyte proliferation; and positive regulation of amyloid precursor protein biosynthetic process. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PAWR (pro-apoptotic WT1 regulator). [provided by Alliance of Genome Resources, Apr 2022]

Pawr 基因产物(1)

mRNA Protein Name
NM_054056.2 NP_473397.1 PRKC apoptosis WT1 regulator protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12917339 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
12917339 MGI
acts upstream of or within interleukin-2 production IMP
IMP: 通过突变表型推断
12970181 MGI
acts upstream of or within negative regulation of B cell proliferation IMP
IMP: 通过突变表型推断
12970181 MGI
acts upstream of or within negative regulation of T cell proliferation IMP
IMP: 通过突变表型推断
12970181 MGI
acts upstream of or within negative regulation of T cell receptor signaling pathway IMP
IMP: 通过突变表型推断
12970181 MGI
involved in negative regulation of fibroblast proliferation IMP
IMP: 通过突变表型推断
25472717 MGI
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
25472717 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
25472717 MGI
acts upstream of or within positive regulation of amyloid precursor protein biosynthetic process IDA
IDA: 通过直接分析推断
14627703 MGI
involved in positive regulation of cellular senescence IMP
IMP: 通过突变表型推断
25472717 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
25472717 MGI
involved in positive regulation of hydrogen peroxide-mediated programmed cell death IMP
IMP: 通过突变表型推断
25472717 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
25472717 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
14627703 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12917339 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

PRKC apoptosis WT1 regulator protein

prostate apoptosis response 4 protein

Pawr 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Pawr Q925B0 Dapk3 Mus musculus O54784
Y2H
12917339
种属内
Pawr Q925B0 Dapk3 Mus musculus O54784
CoIP
12917339
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10087 PAWR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21400 Pawr Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pawr NCBI NCBI:5074
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