COX7C - cytochrome c oxidase subunit 7C Gene

中文名称：细胞色素 c 氧化酶亚基 7C

种属: Homo sapiens

关于 COX7C

功能概要

细胞色素 c 氧化酶 (COX) 是线粒体呼吸链的末端组分，它催化电子从还原的细胞色素 c 转移到氧气。该组分是由线粒体基因编码的 3 个催化亚基和核基因编码的多个结构亚基组成的异聚复合物。线粒体编码的亚基在电子传递中起作用，而核编码的亚基可能在复合物的调节和组装中起作用。该核基因编码 VIIc 亚基，其与小鼠和牛 COX VIIc 的氨基酸序列同一性分别为 87% 和 85%，并且存在于所有组织中。在 13 号染色体上发现了假基因 COX7CP1。[RefSeq 提供，2008 年 7 月]

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13. [provided by RefSeq, Jul 2008]