2. Gene
  3. Fzd5 - frizzled class receptor 5 Gene

Fzd5 - frizzled class receptor 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fz5; Fz-5; mFz5; 5330434N09Rik

基因 ID: 14367 | 基因类型: protein coding

关于 Fzd5

功能概要

Enables Wnt-protein binding activity. Involved in camera-type eye development; canonical Wnt signaling pathway; and positive regulation of cytokine production. Acts upstream of or within several processes, including chorionic trophoblast cell differentiation; embryonic organ development; and positive regulation of nitrogen compound metabolic process. Located in several cellular components, including Golgi apparatus; bicellular tight junction; and perinuclear region of cytoplasm. Colocalizes with early endosome. Is expressed in several structures, including alimentary system; early conceptus; future brain; genitourinary system; and sensory organ. Orthologous to human FZD5 (Frizzled class receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

Fzd5 基因产物(2)

mRNA Protein Name
NM_001042659.2 NP_001036124.1 frizzled-5 precursor
NM_022721.4 NP_073558.2 frizzled-5 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt-protein binding IPI
IPI: 通过物理相互作用推断
18606138 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11520064 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell differentiation in thymus IMP
IMP: 通过突变表型推断
11265645 MGI
acts upstream of or within Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
11092808 MGI
acts upstream of or within angiogenesis IMP
IMP: 通过突变表型推断
11092808 MGI
acts upstream of or within apoptotic process involved in morphogenesis IMP
IMP: 通过突变表型推断
18791178 MGI
acts upstream of or within branching involved in labyrinthine layer morphogenesis IMP
IMP: 通过突变表型推断
23610556 MGI
involved in canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
11265645 MGI
acts upstream of or within chorionic trophoblast cell differentiation IMP
IMP: 通过突变表型推断
23610556 MGI
acts upstream of or within embryonic camera-type eye development IMP
IMP: 通过突变表型推断
18791178 MGI
involved in embryonic camera-type eye morphogenesis IMP
IMP: 通过突变表型推断
18832390 MGI
acts upstream of or within glandular epithelial cell maturation IMP
IMP: 通过突变表型推断
15778706 MGI
acts upstream of or within intestinal epithelial cell maturation IMP
IMP: 通过突变表型推断
15778706 MGI
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: 通过突变表型推断
11092808 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
18791178 MGI
acts upstream of or within positive regulation of JUN kinase activity IDA
IDA: 通过直接分析推断
15195140 MGI
involved in positive regulation of interleukin-1 beta production IGI
IGI: 通过遗传相互作用推断
21857966 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
23610556 MGI
involved in positive regulation of tumor necrosis factor production IGI
IGI: 通过遗传相互作用推断
21857966 MGI
acts upstream of or within post-embryonic camera-type eye development IMP
IMP: 通过突变表型推断
18791178 MGI
involved in post-embryonic camera-type eye development IMP
IMP: 通过突变表型推断
18832390 MGI
acts upstream of or within regulation of bicellular tight junction assembly IMP
IMP: 通过突变表型推断
23610556 MGI
acts upstream of or within regulation of chorionic trophoblast cell proliferation IMP
IMP: 通过突变表型推断
23610556 MGI
acts upstream of or within syncytiotrophoblast cell differentiation involved in labyrinthine layer development IMP
IMP: 通过突变表型推断
23610556 MGI
acts upstream of or within vasculature development IMP
IMP: 通过突变表型推断
18791178 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
11520064 MGI
located in bicellular tight junction IDA
IDA: 通过直接分析推断
23610556 MGI
colocalizes with early endosome IDA
IDA: 通过直接分析推断
16890161 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
11520064 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11520064 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

frizzled-5

frizzled homolog 5

Fzd5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Fzd5 Q9EQD0 Gopc Mus musculus Q8BH60
Anti Tag CoIP
11520064
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 Fzd5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74136 Frizzled-5 Protein, Mouse (CHO, Fc) Q9EQD0 (A27-P167) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-D1474 WNT7A-IN-1 sodium Inhibitor 98.05% 否
HY-170411 WNT7A-IN-1 Inhibitor / 否
HY-RS05181 FZD5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18360 Fzd5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24839 Fzd5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fzd5 NCBI NCBI:7855
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