2. Gene
  3. KRT25 - keratin 25 Gene

KRT25 - keratin 25 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：角蛋白 25

种属: Homo sapiens

同用名: ARWH3; KRT25A; KRT24IRS1

基因 ID: 147183 | 基因类型: protein coding

关于 KRT25

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:40,748,021-40,755,542 (from NCBI)

This gene has 1 transcript (splice variant), 84 orthologues, 68 paralogues and is associated with 2 phenotypes. Low expression observed in reference dataset.

功能概要

该基因编码 I 型 (酸性) 角蛋白家族的成员，属于中间丝 (IF) 蛋白超家族。角蛋白是形成中间丝的杂聚结构蛋白。这些细丝与肌动蛋白微丝和微管一起构成了上皮细胞的细胞骨架。 I 型角蛋白基因聚集在染色体 17q12-q21 的区域。[RefSeq 提供，2009 年 7 月]

This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the Cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]

KRT25 基因产物(1)

mRNA Protein Name
NM_181534.4 NP_853512.1 keratin, type I cytoskeletal 25

KRT25 蛋白结构

Filament

Filament: Intermediate filament protein (78 - 391)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 450 a.a.
蛋白主名 其他名称

keratin, type I cytoskeletal 25

CK-25

关联疾病

疾病名称 别名
Woolly Hair, Autosomal Recessive 3

ARWH3

Woolly Hair, Autosomal Recessive 3, With Hypotrichosis

Autosomal Recessive Woolly Hair 3

Woolly Hair Autosomal Recessive 3
Hypotrichosis 8

HYPT8

Lah3

Hypotrichosis, Localized, Autosomal Recessive 3

Woolly Hair, Autosomal Recessive 1, With Or Without Hypotrichosis

Autosomal Recessive Woolly Hair 1, With Or Without Hypotrichosis

Hypotrichosis Localized Autosomal Recessive 3

Woolly Hair Autosomal Recessive 1 With Or Without Hypotrichosis

ARWH1

Hypotrichosis, Type 8
Familial Woolly Hair Syndrome

Wooly Hair

Familial Wooly Hair Syndrome

Hereditary Woolly Hair Syndrome

Hereditary Wooly Hair Syndrome

Woolly Hair

Syndrome With Woolly Hair

Wooly Hair Syndrome
Hypotrichosis
Hypotrichosis 7

Woolly Hair, Autosomal Recessive 2, With Or Without Hypotrichosis

HYPT7

Hypotrichosis, Localized, Autosomal Recessive 2

Lah2

Ah

Total Hypotrichosis, Mari Type

Wh/Ht

Hypotrichosis, Autosomal Recessive

Hypotrichosis, Total, Mari Type

Woolly Hair, Autosomal Recessive 2 With Or Without Hypotrichosis

Total Mari Type Hypotrichosis

Alopecia Universalis Congenita, Mari Type

Mari Type Alopecia Universalis Congenita

Autosomal Recessive Hypotrichosis

Autosomal Recessive Localized Hypotrichosis

Autosomal Recessive Woolly Hair With Or Without Hypotrichosis

Htl

Hypotrichoses

Hypotrichosis

Lah

Alopecia Universalis Congenita Mari Type

Hypotrichosis Autosomal Recessive

Hypotrichosis Localized Autosomal Recessive 2

Total Hypotrichosis Mari Type

Woolly Hair Autosomal Recessive 2

ARWH2

Woolly Hair Autosomal Recessive 2 With Or Without Hypotrichosis
Hypotrichosis 13

HYPT13

Hypotrichosis With Woolly Hair

Hypotrichosis, Type 13
Epidermolytic Hyperkeratosis

Bullous Congenital Ichthyosiform Erythroderma

Bullous Ichthyosiform Erythroderma

EHK

Bullous Erythroderma Ichthyosiformis Congenita Of Brocq

Bcie

Bie

Epidermolytic Ichthyosis

Ichthyosis Bullosa Of Siemens

Superficial Epidermolytic Ichthyosis

Hyperkeratosis, Epidermolytic

Congenital Bullous Ichthyosiform Erythroderma

Bullous Type Ichthyosis

Epidermolytic Palmoplantar Hyperkeratosis

Bullous Ichthyosiform Erythroderma Congenita

Bullous Erythroderma Ichthyosiforme

Sei

Epidermolytic Hyperkeratosis Late-Onset

Epidermolytic Hyperkeratosis, Late-Onset
Combined Oxidative Phosphorylation Deficiency 16

COXPD16

Infantile Hypertrophic Cardiomyopathy Due To Mrpl44 Deficiency

Combined Oxidative Phosphorylation Defect Type 16

Combined Oxidative Phosphorylation Deficiency, Type 16
Woolly Hair, Autosomal Dominant

Autosomal Dominant Woolly Hair

ADWH

Woolly Hair Autosomal Dominant
Naegeli-Franceschetti-Jadassohn Syndrome

Naegeli Syndrome

Nfj Syndrome

NFJS

Reticular Skin Changes, Dental Anomalies, Decreased Function Of Sweat Glands, Strabismus, And Optic Atrophy

Naegeli-Franceschetti-Jadassohn Syndrome/Dermatopathia Pigmentosa Reticularis

Dpr

Franceschetti-Jadassohn Syndrome

Nfjs/Dpr
Monilethrix

Beaded Hair

MNLIX

Nodose Hair

Moniliform Hair Syndrome
Steatocystoma Multiplex

Sebocystomatosis

Multiple Sebaceous Cysts

Multiplex Steatocystoma

Sebaceous Cysts, Multiple

SM
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07449 KRT25 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus KRT25 RGD RGD:1359097
Felis catus KRT25 VGNC VGNC:108194
Mus musculus KRT25 MGD MGI:1918060
Macaca mulatta KRT25 VGNC VGNC:74167
Bos taurus KRT25 VGNC VGNC:30724
Canis familiaris KRT25 VGNC VGNC:49880
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