KRT78 - keratin 78 Gene

中文名称：角蛋白 78

种属: Homo sapiens

同用名: K5B; K78; Kb40; CK-78

关于 KRT78

功能概要

该基因是 II 型角蛋白基因家族的成员，编码具有中间丝结构域的蛋白质。角蛋白是上皮细胞中的主要结构蛋白，形成 10 至 12 nm 宽的中间丝状细胞质网络，并形成支架，使细胞能够承受机械和非机械应力。 II 型角蛋白家族的基因作为基因簇位于 12p13.13。已鉴定出该基因家族的四个假基因。[RefSeq 提供，2008 年 7 月]

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified. [provided by RefSeq, Jul 2008]