2. Gene
  3. Hdac10 - histone deacetylase 10 Gene

Hdac10 - histone deacetylase 10 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：组蛋白脱乙酰酶 10

种属: Mus musculus

同用名: Hd10

基因 ID: 170787 | 基因类型: protein coding

关于 Hdac10

Chromosome 15: 89,007,510-89,012,903 reverse strand.GRCm39:CM001008.3

This gene has 8 transcripts (splice variants), 181 orthologues, 10 paralogues and is associated with 3 phenotypes. Ubiquitous expression in spleen adult (RPKM 3.7), thymus adult (RPKM 25.1) and 28 other tissues.

功能概要

预测该基因编码的蛋白可启动组蛋白脱乙酰酶活性和组蛋白脱乙酰酶结合活性。预计参与多个过程，包括同源重组；大分子脱酰；和调节含核碱基的化合物代谢过程。预测作用于组蛋白去乙酰化的上游或内部。预测位于细胞质和核质中。预计是组蛋白脱乙酰酶复合物的一部分。以多种结构表达，包括消化系统；眼睛;泌尿生殖系统；免疫系统;和神经系统。与人类 HDAC10（组蛋白脱乙酰酶 10）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable histone deacetylase activity and histone deacetylase binding activity. Predicted to be involved in several processes, including homologous recombination; macromolecule deacylation; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within histone deacetylation. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of histone deacetylase complex. Is expressed in several structures, including alimentary system; eye; genitourinary system; immune system; and nervous system. Orthologous to human HDAC10 (histone deacetylase 10). [provided by Alliance of Genome Resources, Apr 2022]

Hdac10 基因产物(1)

mRNA Protein Name
NM_199198.2 NP_954668.2 polyamine deacetylase HDAC10

Hdac10 蛋白结构

Arginase_HDAC

Arginase_HDAC: cl17011 (17 - 353)

  • 0
  • 200
  • 400
  • 600
  • 666 a.a.
蛋白主名 其他名称

polyamine deacetylase HDAC10

相关产品

Approval
生物活性分子 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-109015 Tucidinostat Inhibitor 98.70% 否
HY-13322 Pracinostat Inhibitor 99.82% 是
HY-B0494 Bufexamac Inhibitor ≥98.0% 否
Clinical Phase
生物活性分子 (11)
目录号 产品名 作用方式
纯度 Phase
HY-10990 Abexinostat Inhibitor 98.61% Phase 3
HY-14842B Givinostat hydrochloride monohydrate Inhibitor ≥98.0% Phase 3
HY-14842 Givinostat Inhibitor 98.05% Phase 3
HY-14842A Givinostat hydrochloride Inhibitor / Phase 3
HY-15433 Quisinostat Inhibitor 98.34% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-15433A Quisinostat dihydrochloride Inhibitor 98.28% Phase 2
HY-16012A Domatinostat Inhibitor 99.43% Phase 2
HY-16012 Domatinostat tosylate Inhibitor 99.66% Phase 2
HY-101780 Tinostamustine Inhibitor 99.42% Phase 2
HY-10223 CUDC-101 Inhibitor 99.19% Phase 1
Pre-clinical Phase
生物活性分子 (26)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13428 Tubacin Inhibitor 95.50% 否
HY-15224 PCI-34051 Inhibitor 99.69% 否
HY-18613 CAY10603 Inhibitor ≥98.0% 否
HY-16699 Nexturastat A Inhibitor 99.03% 否
HY-115475 SW-100 Inhibitor 99.59% 否
HY-111818 TH34 Inhibitor 98.41% 否
HY-19747 HPOB Inhibitor 99.80% 否
HY-144779 HDAC10-IN-1 Inhibitor 99.11% 否
HY-110280 MC1742 Inhibitor 99.20% 否
HY-150109 Purinostat mesylate Inhibitor / 否
HY-149283 JAK/HDAC-IN-2 Inhibitor / 否
HY-152226 MC2590 Inhibitor / 否
HY-152174 HDAC-IN-52 Inhibitor / 否
HY-163430 HDAC-IN-71 Inhibitor / 否
HY-147966 HDAC-IN-43 Inhibitor / 否
HY-150595 HDAC6-IN-10 Inhibitor / 否
HY-152225 MC2625 Inhibitor / 否
HY-157740 XSJ-10 Inhibitor / 否
HY-19754A CRA-026440 hydrochloride Inhibitor 98.14% 否
HY-146684 HDAC-IN-36 Inhibitor / 否
HY-152173 HDAC-IN-51 Inhibitor / 否
HY-147731 HDAC6-IN-9 Inhibitor / 否
HY-15144B (S)-Trichostatin A Inhibitor / 否
HY-109015S Tucidinostat-d4 Inhibitor / 否
HY-144782 HDAC10-IN-2 Inhibitor / 否
HY-19754 CRA-026440 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hdac10 NCBI NCBI:83933
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