2. Gene
  3. Trpm8 - transient receptor potential cation channel, subfamily M, member 8 Gene

Trpm8 - transient receptor potential cation channel, subfamily M, member 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CMR1

基因 ID: 171384 | 基因类型: protein coding

关于 Trpm8

功能概要

Enables ion channel activity. Involved in response to cold. Predicted to be located in external side of plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human TRPM8 (transient receptor potential cation channel subfamily M member 8). [provided by Alliance of Genome Resources, Apr 2022]

Trpm8 基因产物(1)

mRNA Protein Name
NM_134371.3 NP_599198.2 transient receptor potential cation channel subfamily M member 8
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
20214891 RGD
enables monoatomic ion channel activity IDA
IDA: 通过直接分析推断
11882888 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
22750945 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium ion transmembrane transport IDA
IDA: 通过直接分析推断
11882888 RGD
involved in response to cold IDA
IDA: 通过直接分析推断
11882888 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane raft IDA
IDA: 通过直接分析推断
19176480 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transient receptor potential cation channel subfamily M member 8

cold menthol receptor 1

相关产品

Approval
生物活性分子 (4)
目录号 产品名 作用方式
纯度 是否罕见病
HY-75161 (-)-Menthol Activator 99.79% 否
HY-B0985 Phenazopyridine hydrochloride Antagonist 99.84% 否
HY-B1173 (+)-Camphor Inhibitor ≥98.0% 否
HY-B0985A Phenazopyridine Antagonist 99.93% 否
Clinical Phase
生物活性分子 (6)
目录号 产品名 作用方式
纯度 Phase
HY-108449 Acoltremon Agonist 99.13% Phase 3
HY-109087 Elismetrep Antagonist 99.42% Phase 2
HY-112703 AMG 333 Antagonist 99.82% Phase 1
HY-16162A D-3263 hydrochloride Agonist 98.03% Phase 1
HY-115506 PF-05105679 Antagonist 99.84% Phase 1
HY-16162 D-3263 Agonist / Phase 1
Pre-clinical Phase
生物活性分子 (32)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-11062 Icilin Agonist 99.26% 否
HY-100345 AMTB hydrochloride Inhibitor 99.18% 否
HY-101507 Zerencotrep Inhibitor 99.47% 否
HY-19960 BCTC 99.66% 否
HY-18662 RQ-00203078 Antagonist 99.84% 否
HY-N8264 Moringin Agonist 99.95% 否
HY-112430 TRPM8 antagonist 2 Antagonist 98.01% 否
HY-19976 RN-1747 Agonist 99.27% 否
HY-144372 TRPV1 antagonist 3 Antagonist 98.97% 否
HY-110181 M8-B Antagonist 99.89% 否
HY-104059 AMG2850 Antagonist 99.89% 否
HY-145124 TRPM8 antagonist 3 Antagonist 99.51% 否
HY-110199 TC-I 2014 Antagonist ≥99.0% 否
HY-N7117 1,4-Cineole Activator ≥95.0% 否
HY-W014394 Vanillyl butyl ether Agonist 99.67% 否
HY-160900 RN-1665 Antagonist 99.93% 否
HY-126593 Cryosim-3 99.90% 否
HY-130074 FEMA 4809 Agonist 99.25% 否
HY-W014325 TRPM8 agonist WS-3 Agonist 99.35% 否
HY-108461 TRPM8-IN-1 Inhibitor / 否
HY-N7536 Voacangine 98.78% 否
HY-104061 AMG8788 Antagonist / 否
HY-104062 AMG9678 Antagonist / 否
HY-15056 AMG 9090 Agonist / 否
HY-174825 TRPM8 antagonist 4 / 否
HY-174846 TRPM8 antagonist 4 prodrug / 否
HY-RS15118 TRPM8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W711474 (-)-Menthol-d4 / 否
HY-N1369S1 Menthol-d2 Modulator / 否
HY-N9484S Menthofuran-13C2 / 否
HY-RS16771 Trpm8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23211 Trpm8 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trpm8 NCBI NCBI:79054
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