2. Gene
  3. Stim1 - stromal interaction molecule 1 Gene

Stim1 - stromal interaction molecule 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SIM

基因 ID: 20866 | 基因类型: protein coding

关于 Stim1

功能概要

Enables identical protein binding activity. Acts upstream of or within myotube differentiation and store-operated calcium entry. Located in endoplasmic reticulum. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; gonad; hemolymphoid system gland; and musculature. Human ortholog(s) of this gene implicated in Stormorken syndrome; immunodeficiency 10; and tubular aggregate myopathy 1. Orthologous to human STIM1 (stromal interaction molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Stim1 基因产物(4)

mRNA Protein Name
NM_001374058.1 NP_001360987.1 stromal interaction molecule 1 isoform 2 precursor
NM_001374060.1 NP_001360989.1 stromal interaction molecule 1 isoform 3 precursor
NM_001400557.1 NP_001387486.1 stromal interaction molecule 1 isoform 4 precursor
NM_009287.5 NP_033313.2 stromal interaction molecule 1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium channel regulator activity IDA
IDA: 通过直接分析推断
18452988 MGI
enables calcium channel regulator activity IMP
IMP: 通过突变表型推断
31664108 MGI
enables channel activator activity IDA
IDA: 通过直接分析推断
18452988 MGI
enables channel activator activity IMP
IMP: 通过突变表型推断
31664108 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
20037597 MGI
enables ion channel regulator activity involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
18452988 MGI
enables ion channel regulator activity involved in G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
31664108 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11463338 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
17647013 MGI
involved in ion channel modulating, G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
18452988 MGI
involved in ion channel modulating, G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
30131394 MGI
involved in ligand-gated ion channel signaling pathway IDA
IDA: 通过直接分析推断
18452988 MGI
involved in ligand-gated ion channel signaling pathway IMP
IMP: 通过突变表型推断
30131394 MGI
acts upstream of or within monoatomic cation transport IMP
IMP: 通过突变表型推断
17647013 MGI
acts upstream of or within myotube differentiation IMP
IMP: 通过突变表型推断
23206701 MGI
involved in phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway IDA
IDA: 通过直接分析推断
18452988 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
30131394 MGI
involved in positive regulation of insulin secretion IDA
IDA: 通过直接分析推断
18452988 MGI
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
30131394 MGI
acts upstream of or within store-operated calcium entry IGI
IGI: 通过遗传相互作用推断
17343823 MGI
acts upstream of or within store-operated calcium entry IMP
IMP: 通过突变表型推断
31637311 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
23840669 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
18452988 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

stromal interaction molecule 1

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-101942 Zegocractin Inhibitor 99.96% Phase 2
Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19408 Pyr10 Inhibitor 99.95% 否
HY-100932 ML-9 Inhibitor 99.86% 否
HY-N1353 Rhamnocitrin Inhibitor 99.67% 否
HY-113618B RO2959 monohydrochloride Inhibitor 98.19% 否
HY-113618A RO2959 hydrochloride Inhibitor / 否
HY-RS13913 STIM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-100932A ML-9 Free Base Inhibitor / 否
HY-103071 GSK-5503A Inhibitor / 否
HY-RS16865 Stim1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23306 Stim1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Stim1 NCBI NCBI:6786
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