Rho - rhodopsin Gene

种属: Rattus norvegicus

基因 ID: 24717 | 基因类型: protein coding

关于 Rho

功能概要

Enables retinal binding activity and spectrin binding activity. Involved in red, far-red light phototransduction and rhodopsin mediated signaling pathway. Located in photoreceptor outer segment membrane and rough endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital stationary night blindness autosomal dominant 1; fundus albipunctatus; night blindness; retinitis pigmentosa; and retinitis pigmentosa 4. Orthologous to human RHO (rhodopsin). [provided by Alliance of Genome Resources, Apr 2022]

Rho 基因产物(1)

mRNA	Protein	Name
NM_033441.1	NP_254276.1	rhodopsin

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables retinal binding	IDA IDA: 通过直接分析推断	2525480	RGD
enables spectrin binding	IDA IDA: 通过直接分析推断	23704327	RGD

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in G protein-coupled opsin signaling pathway	IDA IDA: 通过直接分析推断	8814134	RGD
involved in red, far-red light phototransduction	IDA IDA: 通过直接分析推断	2525480	RGD

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in photoreceptor outer segment	IDA IDA: 通过直接分析推断	8814134	RGD
located in photoreceptor outer segment membrane	IDA IDA: 通过直接分析推断	2209754	RGD
located in rough endoplasmic reticulum membrane	IDA IDA: 通过直接分析推断	2525480	RGD

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

rhodopsin

Rhodopsin (retinitis pigmentosa 4, autosomal dominant)

相关产品

Approval

生物活性分子 (7)

目录号	产品名	作用方式	纯度	是否罕见病
HY-10583	Y-27632 dihydrochloride	Inhibitor	99.98%	否
HY-10583R	Y-27632 dihydrochloride (Standard)	Inhibitor	99.99%	否
HY-12798	Netarsudil	Inhibitor	99.94%	否
HY-12798B	Netarsudil hydrochloride	Inhibitor	99.90%	否
HY-12798A	Netarsudil dimesylate		99.90%	否
HY-B0515	Ibandronate Sodium Monohydrate	Inducer	98.0%	否
HY-B0515B	Ibandronate Sodium	Inducer	/	否

Clinical Phase

生物活性分子 (5)

目录号	产品名	作用方式	纯度	Phase
HY-109191	Sovesudil	Inhibitor	99.91%	Phase 3
HY-109191A	Sovesudil hydrochloride	Inhibitor	99.45%	Phase 3
HY-113225B	Guanosine triphosphate tritris		/	Phase 3
HY-148808	Zelasudil	Inhibitor	99.33%	Phase 2
HY-I0400	N-Acetylneuraminic acid		99.95%	Phase 1

Pre-clinical Phase

生物活性分子 (63)

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-15392	Chroman 1	Inhibitor	99.42%	否
HY-12755	ML141		99.96%	否
HY-12646	Rhosin hydrochloride		99.94%	否
HY-16563	Narciclasine	Activator	99.88%	否
HY-17543	ML-323	Inhibitor	99.51%	否
HY-10583G	Y-27632 dihydrochloride (GMP)	Inhibitor	/	否
HY-13991	CCG-1423		99.88%	否
HY-111458	GSK2643943A	Inhibitor	98.79%	否
HY-104064	1A-116		99.72%	否
HY-108361	CCG-203971	Inhibitor	99.89%	否
HY-115376	Z62954982	Inhibitor	99.38%	否
HY-12649	Y16	Inhibitor	98.10%	否
HY-12646A	Rhosin		95.08%	否
HY-121750	CCG-222740	Inhibitor	99.53%	否
HY-134817	USP7-IN-8	Inhibitor	99.04%	否
HY-N6012	(-)-Alkannin	Inducer	99.88%	否
HY-108518	SB-772077B dihydrochloride	Inhibitor	99.33%	否
HY-18990	GSK180736A	Inhibitor	98.81%	否
HY-150640	Rho-Kinase-IN-2	Inhibitor	98.80%	否
HY-N2438	Methylophiopogonanone B	Activator	99.84%	否
HY-100270	Rho-Kinase-IN-1	Inhibitor	99.91%	否
HY-15392A	Chroman 1 dihydrochloride	Inhibitor	99.11%	否
HY-117149	MLS000532223	Inhibitor	98.45%	否
HY-111432	CCG-232601	Inhibitor	99.00%	否
HY-139170	CAY10746	Inhibitor	98.61%	否
HY-W050122	S-(+)-GABOB		95.0%	否
HY-112362	3-(4-Pyridyl)indole	Inhibitor	99.0%	否
HY-122011	PF-4950834	Inhibitor	99.60%	否
HY-126913	Rhodblock 6	Inhibitor	98.94%	否
HY-152095	PPI-GIT1/β-Pix PPI-IN-1	Inhibitor	99.01%	否
HY-15720B	Glycyl H-1152 hydrochloride	Inhibitor	99.9%	否
HY-P2325	Exoenzyme C3, clostridium botulinum	Inhibitor	/	否
HY-103045A	CMPD101 hydrochloride	Inhibitor	/	否
HY-118046	GSK2163632A	Inhibitor	/	否
HY-118151	Rho-Kinase-IN-3	Inhibitor	/	否
HY-118837	WF-536	Inhibitor	/	否
HY-120429	SKLB-163	Inducer	/	否
HY-123345	CRT 0105446	Inhibitor	/	否
HY-129907	2-AEMP		/	否
HY-130011	CCG-232964	Inhibitor	/	否
HY-134913	Rhodblock 1a	Inhibitor	/	否
HY-137638	Sp-5,6-DCl-cBIMPS	Activator	/	否
HY-137638A	Sp-5,6-DCl-cBIMPS sodium	Activator	/	否
HY-138147	DCP-Rho1		/	否
HY-13991A	(S)-CCG-1423		/	否
HY-145294	ROCK2-IN-5	Inhibitor	/	否
HY-171909A	Glycerophosphoinositol 4-phosphate disodium		/	否
HY-172917	Rho GTPase inhibitor 1	Inhibitor	/	否
HY-173222	P-gp inhibitor 28	Inhibitor	/	否
HY-N10341	Centaureidin	Activator	/	否
HY-P5158	Conopeptide rho-TIA	Inhibitor	/	否
HY-P5467	S6(229-239), Amide, biotinalyted	Substrate	/	否
HY-RS11944	RHO Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS11951	RHOD Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-W047432	5-Nitro-1H-indazole-3-carbonitrile	Inhibitor	/	否
HY-W110138	Chloroxoquinoline		/	否
HY-130448	8-iso Prostaglandin F1β		/	否
HY-158652	(R)-CCG-1423	Inhibitor	/	否
HY-P10393	ERα17p	Inducer	/	否
HY-P10636	Nictide		/	否
HY-RS17157	Rho Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS22304	Rhod Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS23607	Rho Rat Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Homo sapiens	Rho	NCBI	NCBI:6010
Canis familiaris	Rho	NCBI	NCBI:493763
Mus musculus	Rho	NCBI	NCBI:212541

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