2. Gene
  3. Rho - rhodopsin Gene

Rho - rhodopsin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ops; RP4; Opn2; Noerg1

基因 ID: 212541 | 基因类型: protein coding

关于 Rho

功能概要

Predicted to enable G protein-coupled photoreceptor activity; retinal binding activity; and spectrin binding activity. Involved in photoreceptor cell maintenance. Acts upstream of or within several processes, including detection of temperature stimulus involved in thermoception; thermotaxis; and visual perception. Located in several cellular components, including photoreceptor inner segment; sperm head plasma membrane; and sperm midpiece. Is expressed in several structures, including brain; eye; and heart. Used to study congenital stationary night blindness autosomal dominant 1 and retinitis pigmentosa 4. Human ortholog(s) of this gene implicated in congenital stationary night blindness autosomal dominant 1; fundus albipunctatus; night blindness; retinitis pigmentosa; and retinitis pigmentosa 4. Orthologous to human RHO (rhodopsin). [provided by Alliance of Genome Resources, Apr 2022]

Rho 基因产物(1)

mRNA Protein Name
NM_145383.2 NP_663358.1 rhodopsin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17881533 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to light stimulus IMP
IMP: 通过突变表型推断
21052544 MGI
acts upstream of or within detection of light stimulus IMP
IMP: 通过突变表型推断
11747369 MGI
acts upstream of or within detection of temperature stimulus involved in thermoception IGI
IGI: 通过遗传相互作用推断
31924821 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
32960171 MGI
acts upstream of or within microtubule cytoskeleton organization IMP
IMP: 通过突变表型推断
15976449 MGI
acts upstream of or within photoreceptor cell maintenance IMP
IMP: 通过突变表型推断
22183357 MGI
involved in photoreceptor cell maintenance IMP
IMP: 通过突变表型推断
32312889 MGI
acts upstream of or within phototransduction IMP
IMP: 通过突变表型推断
16723493 MGI
acts upstream of or within podosome assembly IMP
IMP: 通过突变表型推断
15976449 MGI
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
10097103 MGI
acts upstream of or within response to light intensity IMP
IMP: 通过突变表型推断
32960171 MGI
acts upstream of or within response to light stimulus IMP
IMP: 通过突变表型推断
16723493 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: 通过突变表型推断
21052544 MGI
acts upstream of or within rod bipolar cell differentiation IMP
IMP: 通过突变表型推断
32960171 MGI
acts upstream of or within sensory perception of light stimulus IMP
IMP: 通过突变表型推断
16723493 MGI
acts upstream of or within thermotaxis IGI
IGI: 通过遗传相互作用推断
31924821 MGI
acts upstream of or within visual perception IMP
IMP: 通过突变表型推断
22937111 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
23793062 MGI
located in photoreceptor inner segment IDA
IDA: 通过直接分析推断
10399916 MGI
located in photoreceptor outer segment IDA
IDA: 通过直接分析推断
10725384 MGI
located in rod photoreceptor outer segment IDA
IDA: 通过直接分析推断
19332056 MGI
located in sperm head plasma membrane IDA
IDA: 通过直接分析推断
31924821 MGI
located in sperm midpiece IDA
IDA: 通过直接分析推断
31924821 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

rhodopsin

L opsin

LWS opsin

long wavelength sensitive opsin

opsin 2

red opsin

rod opsin

相关产品

Approval
生物活性分子 (7)
目录号 产品名 作用方式
纯度 是否罕见病
HY-10583 Y-27632 dihydrochloride Inhibitor 99.98% 否
HY-10583R Y-27632 dihydrochloride (Standard) Inhibitor / 否
HY-12798B Netarsudil hydrochloride Inhibitor 99.90% 否
HY-12798 Netarsudil Inhibitor 99.94% 否
HY-12798A Netarsudil dimesylate 99.90% 否
HY-B0515 Ibandronate Sodium Monohydrate Inducer ≥98.0% 否
HY-B0515B Ibandronate Sodium Inducer / 否
Clinical Phase
生物活性分子 (5)
目录号 产品名 作用方式
纯度 Phase
HY-109191 Sovesudil Inhibitor 99.91% Phase 3
HY-109191A Sovesudil hydrochloride Inhibitor 99.45% Phase 3
HY-113225B Guanosine triphosphate tritris / Phase 3
HY-148808 Zelasudil Inhibitor 99.33% Phase 2
HY-I0400 N-Acetylneuraminic acid 99.90% Phase 1
Pre-clinical Phase
生物活性分子 (61)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15392 Chroman 1 Inhibitor 99.42% 否
HY-12755 ML141 99.96% 否
HY-12646 Rhosin hydrochloride 99.93% 否
HY-16563 Narciclasine Activator 99.88% 否
HY-17543 ML-323 Inhibitor 99.51% 否
HY-13991 CCG-1423 99.88% 否
HY-10583G Y-27632 dihydrochloride (GMP) Inhibitor / 否
HY-111458 GSK2643943A Inhibitor 98.79% 否
HY-104064 1A-116 99.72% 否
HY-108361 CCG-203971 Inhibitor 99.89% 否
HY-121750 CCG-222740 Inhibitor 99.53% 否
HY-115376 Z62954982 Inhibitor 99.38% 否
HY-12649 Y16 Inhibitor 98.10% 否
HY-134817 USP7-IN-8 Inhibitor 99.04% 否
HY-108518 SB-772077B dihydrochloride Inhibitor 99.33% 否
HY-18990 GSK180736A Inhibitor 98.81% 否
HY-N6012 (-)-Alkannin Inducer 99.88% 否
HY-150640 Rho-Kinase-IN-2 Inhibitor 99.29% 否
HY-N2438 Methylophiopogonanone B Activator 99.84% 否
HY-100270 Rho-Kinase-IN-1 Inhibitor 99.91% 否
HY-117149 MLS000532223 Inhibitor 99.46% 否
HY-139170 CAY10746 Inhibitor 98.61% 否
HY-111432 CCG-232601 Inhibitor 99.00% 否
HY-W050122 S-(+)-GABOB ≥95.0% 否
HY-12646A Rhosin 95.08% 否
HY-15392A Chroman 1 dihydrochloride Inhibitor 99.11% 否
HY-112362 3-(4-Pyridyl)indole Inhibitor ≥99.0% 否
HY-122011 PF-4950834 Inhibitor 99.60% 否
HY-126913 Rhodblock 6 Inhibitor 98.94% 否
HY-152095 PPI-GIT1/β-Pix PPI-IN-1 Inhibitor 99.01% 否
HY-103045A CMPD101 hydrochloride Inhibitor / 否
HY-118046 GSK2163632A Inhibitor / 否
HY-118151 Rho-Kinase-IN-3 Inhibitor / 否
HY-118837 WF-536 Inhibitor / 否
HY-120429 SKLB-163 Inducer / 否
HY-123345 CRT 0105446 Inhibitor / 否
HY-129907 2-AEMP / 否
HY-130011 CCG-232964 Inhibitor / 否
HY-134913 Rhodblock 1a Inhibitor / 否
HY-137638 Sp-5,6-DCl-cBIMPS Activator / 否
HY-137638A Sp-5,6-DCl-cBIMPS sodium Activator / 否
HY-138147 DCP-Rho1 / 否
HY-13991A (S)-CCG-1423 / 否
HY-145294 ROCK2-IN-5 Inhibitor / 否
HY-15720B Glycyl H-1152 hydrochloride Inhibitor / 否
HY-171909A Glycerophosphoinositol 4-phosphate disodium / 否
HY-172917 Rho GTPase inhibitor 1 Inhibitor / 否
HY-173222 P-gp inhibitor 28 Inhibitor / 否
HY-N10341 Centaureidin Activator / 否
HY-P2325 Exoenzyme C3, clostridium botulinum / 否
HY-P5158 Conopeptide rho-TIA Inhibitor / 否
HY-P5467 S6(229-239), Amide, biotinalyted Substrate / 否
HY-RS11944 RHO Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS11951 RHOD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-130448 8-iso Prostaglandin F1β / 否
HY-158652 (R)-CCG-1423 Inhibitor / 否
HY-P10393 ERα17p Inducer / 否
HY-P10636 Nictide / 否
HY-RS17157 Rho Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22304 Rhod Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23607 Rho Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rho NCBI NCBI:6010
Canis familiaris Rho NCBI NCBI:493763
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