2. Gene
  3. Cyp1b1 - cytochrome P450, family 1, subfamily b, polypeptide 1 Gene

Cyp1b1 - cytochrome P450, family 1, subfamily b, polypeptide 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25426 | 基因类型: protein coding

关于 Cyp1b1

功能概要

Enables monooxygenase activity. Involved in several processes, including positive regulation of macromolecule biosynthetic process; response to gonadotropin; and response to steroid hormone. Located in nucleus. Biomarker of breast adenocarcinoma and esophagus squamous cell carcinoma. Human ortholog(s) of this gene implicated in Peters anomaly; anterior segment dysgenesis 6; breast cancer; glaucoma (multiple); and lung squamous cell carcinoma. Orthologous to human CYP1B1 (Cytochrome P450 family 1 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp1b1 基因产物(1)

mRNA Protein Name
NM_012940.2 NP_037072.1 cytochrome P450 1B1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables monooxygenase activity IDA
IDA: 通过直接分析推断
15258110 RGD
enables oxidoreductase activity IDA
IDA: 通过直接分析推断
16893557 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA modification IMP
IMP: 通过突变表型推断
24025706 RGD
involved in adrenal gland development IEP
IEP: 通过表达模式推断
10098502 RGD
involved in benzene-containing compound metabolic process IDA
IDA: 通过直接分析推断
9806168 RGD
involved in benzene-containing compound metabolic process IMP
IMP: 通过突变表型推断
24025706 RGD
involved in cellular response to cAMP IEP
IEP: 通过表达模式推断
21389345 RGD
involved in cellular response to cortisol stimulus IEP
IEP: 通过表达模式推断
8674863 RGD
involved in cellular response to luteinizing hormone stimulus IEP
IEP: 通过表达模式推断
21389345 RGD
involved in cellular response to progesterone stimulus IEP
IEP: 通过表达模式推断
8674863 RGD
involved in cellular response to toxic substance IMP
IMP: 通过突变表型推断
31746392 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
10403529 RGD
involved in estrogen metabolic process IDA
IDA: 通过直接分析推断
23821647 RGD
involved in estrogen metabolic process IMP
IMP: 通过突变表型推断
16893557 RGD
involved in estrous cycle IEP
IEP: 通过表达模式推断
12223220 RGD
involved in ganglion development IEP
IEP: 通过表达模式推断
17687037 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
19074971 RGD
involved in positive regulation of DNA biosynthetic process IMP
IMP: 通过突变表型推断
20439821 RGD
involved in positive regulation of apoptotic process IEP
IEP: 通过表达模式推断
18336843 RGD
involved in positive regulation of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
20439821 RGD
involved in positive regulation of smooth muscle cell migration IMP
IMP: 通过突变表型推断
20439821 RGD
involved in positive regulation of translation IMP
IMP: 通过突变表型推断
20439821 RGD
involved in response to 3-methylcholanthrene IEP
IEP: 通过表达模式推断
19889059 RGD
involved in response to arsenic-containing substance IEP
IEP: 通过表达模式推断
23999541 RGD
involved in response to dexamethasone IEP
IEP: 通过表达模式推断
9804617 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
19074971 RGD
involved in response to follicle-stimulating hormone IEP
IEP: 通过表达模式推断
19074971 RGD
involved in response to indole-3-methanol IEP
IEP: 通过表达模式推断
11719698 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
11739881 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
7744798 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
12704664 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
7788849 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytochrome P450 1B1

CYPIB1

P450RAP

cytochrome P450, subfamily 1B, polypeptide 1

cytochrome P450RAP

hydroperoxy icosatetraenoate dehydratase

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B1234 Octinoxate 99.84% 否
HY-W017113 2-Mercaptobenzothiazole Activator 99.85% 是
Pre-clinical Phase
生物活性分子 (32)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19340 TMS Inhibitor 99.40% 否
HY-W007700 8-Bromooctanoic acid 99.89% 否
HY-152118 CYP1B1-IN-4 Inhibitor 99.09% 否
HY-101284 DMU2105 Inhibitor 99.54% 否
HY-101285 DMU2139 Inhibitor 98.0% 否
HY-159006 CYP1B1 ligand 3 Inhibitor 99.83% 否
HY-146393 PROTAC CYP1B1 degrader-1 Inhibitor 98.09% 否
HY-157942 CYP1B1-IN-7 Inhibitor 99.88% 否
HY-RS03443 CYP1B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-150557 CYP1B1-IN-1 Inhibitor / 否
HY-150558 CYP1B1-IN-2 Inhibitor / 否
HY-152079 CYP1B1-IN-3 Inhibitor / 否
HY-152196 CYP1B1-IN-5 Inhibitor / 否
HY-158429 PROTAC CYP1B1 degrader-2 Degrader / 否
HY-158430 CYP1B1 ligand 2 / 否
HY-161403 CYP1B1-IN-8 Inhibitor / 否
HY-162051 CYP1B1-IN-6 Inhibitor / 否
HY-174425 CYP1B1-IN-9 Inhibitor / 否
HY-175554 CYP1B1-IN-10 Inhibitor / 否
HY-175760 CYP1B1-IN-11 Inhibitor / 否
HY-175836 CYP1B1-IN-12 / 否
HY-178053 AHR agonist 10 / 否
HY-W713284 2-Ethylhexyl (E)-3-(4-(methoxy-d3)phenyl)acrylate / 否
HY-101284A (E/Z)-DMU2105 Inhibitor / 否
HY-126308 (E/Z)-DMU2139 Inhibitor / 否
HY-158431 (S,R,S)-AHPC-Me-8-bromooctanoic acid / 否
HY-B1234S Octinoxate-13C,d3 / 否
HY-RS16945 Cyp1b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23388 Cyp1b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W472509 11-HETE Activator / 否
HY-W517092 1,2,3,4,7,8,9-Heptachlorodibenzofuran / 否
HY-W775354 1,2,3,4,7,8-Hexachlorodibenzofuran / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp1b1 NCBI NCBI:1545
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