2. Gene
  3. Traf6 - TNF receptor associated factor 6 Gene

Traf6 - TNF receptor associated factor 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 311245 | 基因类型: protein coding

关于 Traf6

功能概要

Predicted to enable several functions, including enzyme binding activity; tumor necrosis factor receptor binding activity; and ubiquitin protein Ligase activity. Involved in JNK cascade; interleukin-1-mediated signaling pathway; and positive regulation of smooth muscle cell proliferation. Part of protein-containing complex. Orthologous to human TRAF6 (TNF Receptor associated factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Traf6 基因产物(1)

mRNA Protein Name
NM_001107754.2 NP_001101224.1 TNF receptor-associated factor 6
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in JNK cascade IMP
IMP: 通过突变表型推断
15890643 RGD
involved in cellular response to angiotensin IEP
IEP: 通过表达模式推断
27249171 RGD
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
27249171 RGD
involved in cytokine-mediated signaling pathway IMP
IMP: 通过突变表型推断
15890643 RGD
involved in interleukin-1-mediated signaling pathway IMP
IMP: 通过突变表型推断
20967881 RGD
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
15890643 RGD
involved in regulation protein catabolic process at postsynapse IDA
IDA: 通过直接分析推断
28973854 RGD
involved in regulation protein catabolic process at postsynapse IEP
IEP: 通过表达模式推断
28973854 RGD
involved in regulation protein catabolic process at postsynapse IMP
IMP: 通过突变表型推断
28973854 RGD
involved in response to ischemia IEP
IEP: 通过表达模式推断
27538408 RGD
involved in synapse assembly EXP
EXP: 通过实验结果推断
33363141 RGD
involved in synapse assembly IDA
IDA: 通过直接分析推断
33363141 RGD
involved in synapse assembly IMP
IMP: 通过突变表型推断
33363141 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
33363141 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
28973854 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
28973854 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
28973854 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
20967881 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

TNF receptor-associated factor 6

E3 ubiquitin-protein ligase TRAF6

RING-type E3 ubiquitin transferase TRAF6

TNF receptor-associated factor 6, E3 ubiquitin protein ligase

相关产品

Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120934 C25-140 Inhibitor 99.92% 否
HY-110247 TRAF-STOP inhibitor 6877002 Inhibitor 99.67% 否
HY-N1431 Tabersonine 98.14% 否
HY-P3709A TRAF6 peptide TFA Inhibitor 98.20% 否
HY-125025 SMI 6860766 Inhibitor / 否
HY-W013636C 2-Ketoglutaric acid potassium Inhibitor 98.0% 否
HY-164670 D228 99.77% 否
HY-P3709 TRAF6 peptide Inhibitor / 否
HY-176220 GPX4-AUTAC / 否
HY-P11001 RANK-derived TRAF6 inhibitor Inhibitor / 否
HY-P11002 PTD Control / 否
HY-P3708 TRAF6 control peptide Control / 否
HY-RS14975 TRAF6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174520 Human TLR8 mRNA / 否
HY-N1431A Tabersonine hydrochloride / 否
HY-RS16663 Traf6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23098 Traf6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Traf6 NCBI NCBI:7189
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