1. Gene
  2. Panx1 - Pannexin 1 Gene

Panx1 - Pannexin 1 Gene

种属: Rattus norvegicus

同用名: px1

基因 ID: 315435 | 基因类型: protein coding

关于 Panx1

功能概要

The protein encoded by this gene is a plasma membrane protein that is a structural component of gap junctions. The encoded protein acts as a homodimer or as a heterodimer with Other isoforms or proteins. Two additional variants have been found, and the isoforms expressed from them are found in the cytoplasm. It is thought that these two isoforms could attenuate the actions of the membrane-bound protein. [provided by RefSeq, Jul 2012]

Panx1 基因产物(3)

mRNA Protein Name
NM_001270548.1 NP_001257477.1 pannexin-1 isoform c
NM_001270549.1 NP_001257478.1 pannexin-1 isoform d
NM_199397.2 NP_955429.1 pannexin-1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables gap junction channel activity IMP
IMP: 通过突变表型推断
14597722 RGD
NOT enables gap junction hemi-channel activity IDA
IDA: 通过直接分析推断
17715132 RGD
enables protease binding IPI
IPI: 通过物理相互作用推断
19416975 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
19416975 RGD
enables protein-containing complex binding IMP
IMP: 通过突变表型推断
14597722 RGD
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
19416975 RGD
enables structural molecule activity IDA
IDA: 通过直接分析推断
17715132 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
19416975 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell-cell signaling IMP
IMP: 通过突变表型推断
14597722 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
17715132 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
17715132 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pannexin-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Panx1 NCBI NCBI:24145