1. Gene
  2. Rassf5 - Ras association (RalGDS/AF-6) domain family member 5 Gene

Rassf5 - Ras association (RalGDS/AF-6) domain family member 5 Gene

种属: Mus musculus

同用名: Rapl; Maxp1; Nore1; Nore1A; Nore1B; 1300019G20Rik

基因 ID: 54354 | 基因类型: protein coding

关于 Rassf5

功能概要

Predicted to enable identical protein binding activity. Acts upstream of or within negative regulation of cell population proliferation; positive regulation of protein ubiquitination; and regulation of protein localization to nucleus. Located in nucleus. Is expressed in heart and thymus primordium. Used to study systemic lupus erythematosus. Orthologous to human RASSF5 (Ras association domain family member 5). [provided by Alliance of Genome Resources, Apr 2022]

Rassf5 基因产物(3)

mRNA Protein Name
NM_001311094.2 NP_001298023.1 ras association domain-containing protein 5 isoform 2
NM_001313731.1 NP_001300660.1 ras association domain-containing protein 5 isoform 3
NM_018750.4 NP_061220.2 ras association domain-containing protein 5 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9488663 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of lymphocyte proliferation IMP
IMP: 通过突变表型推断
21194982 MGI
acts upstream of or within negative regulation of lymphocyte proliferation IMP
IMP: 通过突变表型推断
21194982 MGI
acts upstream of or within positive regulation of protein ubiquitination IMP
IMP: 通过突变表型推断
22173032 MGI
acts upstream of or within regulation of protein localization to nucleus IMP
IMP: 通过突变表型推断
21194982 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
22173032 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ras association domain-containing protein 5

Rap1-binding protein

new ras effector 1

novel ras effector 1

regulator for cell adhesion and polarization enriched in lymphoid tissues

Rassf5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Rassf5 Q5EBH1 Stk4 Mus musculus Q9JI11 16892067
种属间
Rassf5 Q5EBH1 HRAS Homo sapiens P01112
NMR
16698549
种属间
Rassf5 Q5EBH1 HRAS Homo sapiens P01112 18596699
种属间
Rassf5 Q5EBH1 HRAS Homo sapiens P01112
ITC
16698549
种属间
Rassf5 Q5EBH1 HRAS Homo sapiens P01112 18596699
种属内
Rassf5 Q5EBH1 Hras Mus musculus Q61411 9488663
种属间
Rassf5 Q5EBH1 RAP1A Homo sapiens P62834
ITC
16698549
种属间
Rassf5 Q5EBH1 RAP1A Homo sapiens P62834 12845325
种属内
Rassf5 Q5EBH1 Mdm2 Mus musculus P23804
Y2H
22173032
种属内
Rassf5 Q5EBH1 Hipk1 Mus musculus O88904
Y2H
22173032
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rassf5 NCBI NCBI:83593