2. Gene
  3. Ephx2 - epoxide hydrolase 2 Gene

Ephx2 - epoxide hydrolase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 65030 | 基因类型: protein coding

关于 Ephx2

功能概要

Enables Epoxide Hydrolase activity; magnesium ion binding activity; and Phosphatase activity. Involved in several processes, including linoleic acid metabolic process; prostaglandin production involved in inflammatory response; and sensory perception of pain. Located in cytosol and peroxisome. Used to study cerebral infarction; hypertension; and pulmonary hypertension. Human ortholog(s) of this gene implicated in coronary artery disease; familial hypercholesterolemia; and hypertension. Orthologous to human EPHX2 (Epoxide Hydrolase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ephx2 基因产物(1)

mRNA Protein Name
NM_022936.1 NP_075225.1 bifunctional epoxide hydrolase 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables epoxide hydrolase activity IDA
IDA: 通过直接分析推断
8349641 RGD
enables magnesium ion binding IMP
IMP: 通过突变表型推断
12574508 RGD
enables phosphatase activity IDA
IDA: 通过直接分析推断
12574508 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epoxide metabolic process IDA
IDA: 通过直接分析推断
21217101 RGD
involved in linoleic acid metabolic process IMP
IMP: 通过突变表型推断
16962614 RGD
involved in positive regulation of blood pressure IMP
IMP: 通过突变表型推断
11882632 RGD
involved in prostaglandin production involved in inflammatory response IMP
IMP: 通过突变表型推断
16962614 RGD
involved in response to 3-methylcholanthrene IEP
IEP: 通过表达模式推断
19889059 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in peroxisome IDA
IDA: 通过直接分析推断
3181162 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bifunctional epoxide hydrolase 2

CEH

SEH

cytosolic epoxide hydrolase

epoxide hydratase

epoxide hydrolase 2, cytoplasmic

soluble epoxide hydrolase

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-159157 Anti-inflammatory agent 92 Inhibitor / 否
HY-RS04439 EPHX2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18273 Ephx2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24751 Ephx2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ephx2 NCBI NCBI:2053
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