1. Gene
  2. Dusp6 - dual specificity phosphatase 6 Gene

Dusp6 - dual specificity phosphatase 6 Gene

种属: Mus musculus

同用名: MKP3; MKP-3; PYST1; 1300019I03Rik

基因 ID: 67603 | 基因类型: protein coding

关于 Dusp6

功能概要

Enables phosphoprotein Phosphatase activity. Acts upstream of or within negative regulation of protein phosphorylation; protein dephosphorylation; and regulation of heart growth. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; embryo ectoderm; embryo mesenchyme; renal cortex; and sensory organ. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 19 with or without anosmia. Orthologous to human DUSP6 (dual specificity Phosphatase 6). [provided by Alliance of Genome Resources, Apr 2022]

Dusp6 基因产物(1)

mRNA Protein Name
NM_026268.3 NP_080544.1 dual specificity protein phosphatase 6
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphoprotein phosphatase activity IDA
IDA: 通过直接分析推断
15284227 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15284227 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
18753132 MGI
acts upstream of or within protein dephosphorylation IDA
IDA: 通过直接分析推断
15284227 MGI
acts upstream of or within protein dephosphorylation IMP
IMP: 通过突变表型推断
18753132 MGI
acts upstream of or within regulation of heart growth IMP
IMP: 通过突变表型推断
18753132 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dual specificity protein phosphatase 6

MAP kinase phosphatase 3

mitogen-activated protein kinase phosphatase 3

Dusp6 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Dusp6 Q9DBB1 Mapk1 Mus musculus P63085 16148006
种属内
Dusp6 Q9DBB1 Mapk1 Mus musculus P63085
Y2H
16148006
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dusp6 NCBI NCBI:1848