1. Gene
  2. GGACT - gamma-glutamylamine cyclotransferase Gene

GGACT - gamma-glutamylamine cyclotransferase Gene

中文名称:γ-谷氨酰胺环转移酶

种属: Homo sapiens

同用名: A2LD1

基因 ID: 87769 | 基因类型: protein coding

关于 GGACT

Cytogenetic location: 13q32.3 Genomic coordinates (GRCh38): 13:100,530,180-100,588,789 (from NCBI)

This gene has 7 transcripts (splice variants) and 202 orthologues. Biased expression in kidney (RPKM 12.0), fat (RPKM 1.8) and 13 other tissues.

功能概要

该基因编码的蛋白质通过分解异二肽 L-γ-谷氨酰-L-ε-赖氨酸 (纤维蛋白降解的副产物) 来帮助交联纤维蛋白的蛋白水解降解。编码的γ-谷氨酰胺环转移酶催化的反应产生 5-氧代-L-脯氨酸和游离烷基胺。已发现该基因编码相同蛋白质的两个转录变体。[RefSeq 提供,2010 年 8 月]

The protein encoded by this gene aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the encoded gamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and a free alkylamine. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Aug 2010]

GGACT 基因产物(2)

mRNA Protein Name
NM_001195087.2 NP_001182016.1 gamma-glutamylaminecyclotransferase
NM_033110.3 NP_149101.1 gamma-glutamylaminecyclotransferase

GGACT 蛋白结构

GGACT

GGACT: Gamma-glutamyl cyclotransferase, AIG2-like (4 - 119)

  • 0
  • 100
  • 153 a.a.
蛋白主名 其他名称

gamma-glutamylaminecyclotransferase

AIG2-like domain 1

重组 GGACT 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70902 GGACT Protein, Human (HEK293, His) Q9BVM4 (M1-R153) ≥95%

直系同源

种属 基因名 来源 基因 ID
Mus musculus GGACT MGD MGI:2385008
Rattus norvegicus GGACT RGD RGD:1304748
Canis familiaris GGACT VGNC VGNC:41196
Bos taurus GGACT VGNC VGNC:29338
Felis catus GGACT VGNC VGNC:62535
Macaca mulatta GGACT VGNC VGNC:72781
Others GGACT NCBI