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  3. Guanfacine-d2 hydrochloride

Guanfacine-d2 hydrochloride  (Synonyms: 盐酸胍法辛 d2 (盐酸盐))

目录号: HY-17416S
产品使用指南

Guanfacine-d2 (hydrochloride) 是 Guanfacine hydrochloride 的氘代物。Guanfacine hydrochloride 是α2A肾上腺素受体激动剂,Kd为31 nM,具有抗高血压的活性。

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Guanfacine-d<sub>2</sub> hydrochloride Chemical Structure

Guanfacine-d2 hydrochloride Chemical Structure

CAS No. : 1398065-88-7

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生物活性

Guanfacine-d2 (hydrochloride) is the deuterium labeled Guanfacine hydrochloride. Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

284.57

Formula

C9H8D2Cl3N3O

CAS 号
中文名称

盐酸胍法辛 d2 (盐酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Guanfacine-d2 hydrochloride
目录号:
HY-17416S
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