2. Apoptosis Anti-infection
  3. Apoptosis Parasite
  4. Lactucin

Lactucin  (Synonyms: 莴苣素；山莴苣素)

目录号: HY-N9438
产品使用指南

摩尔计算器

Lactucin 是一种抗炎剂。Lactucin 诱导癌细胞凋亡 (apoptosis)。Lactucin 还显示出缓解疼痛、抗癌和抗疟疾的活性。

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Lactucin Chemical Structure

Lactucin Chemical Structure

CAS No. : 1891-29-8

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3.  试用装只面向终端客户。

规格 是否有货
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100 mg   询价  
250 mg   询价  

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Lactucin 相关抗体

Top Publications Citing Use of Products

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lactucin is an anti-inflammatory agent. Lactucin induces cancer cell apoptosis. Lactucin also shows analgesic, anticancer and antimalarial activities[1][2][3][4].

体外研究
(In Vitro)

Lactucin shows moderate inhibitory activity against LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages[1].
Lactucin (0-100 µM; 24 and 48 h) induces cytotoxic effects in HL-60 cells in a dose– and time-dependent manner[3].
Lactucin (0-100 µM; 48 h) induces apoptosis and sub-G1 cell cycle arrest in HL-60 cells[3].
Lactucin (10 μg/mL; 48 h) completely prevents Plasmodium falciparum parasitemia[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Lactucin 相关抗体:

Cell Viability Assay[3]

Cell Line: HL-60
Concentration: 0, 5, 25, 50, and 100 µM
Incubation Time: 24 and 48 h
Result: Induced significant cytotoxic effects in these cancer cells in a dose– and time-dependent manner.

Apoptosis Analysis[3]

Cell Line: HL-60
Concentration: 0, 5, 50 and 100 µM
Incubation Time: 48 h
Result: Induced apoptosis. Swelling of the mitochondria and endoplasmic reticulum (ER) was detected in the cells.

Cell Cycle Analysis[3]

Cell Line: HL-60
Concentration: 0, 5, 50 and 100 µM
Incubation Time: 48 h
Result: Induced sub-G1 cell cycle arrest.
体内研究
(In Vivo)

Lactucin (15 and 30 mg/kg; i.p.; once) decreases the spontaneous locomotor activity and shows analgesic properties in mice[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Albino-Swiss mice (18-24 g)[2]
Dosage: 15 and 30 mg/kg
Administration: Intraperitoneal injection, once
Result: Decreased the spontaneous locomotor activity and showed analgesic properties in the hot plate test.
分子量

276.28

Formula

C15H16O5
CAS 号
中文名称

莴苣素；山莴苣素
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性数据
In Vitro: 

DMSO 中的溶解度 : ≥ 250 mg/mL (904.88 mM; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.6195 mL 18.0976 mL 36.1952 mL
5 mM 0.7239 mL 3.6195 mL 7.2390 mL
查看完整储备液配制表

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Lactucin 相关分类

完整储备液配制表

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6195 mL 18.0976 mL 36.1952 mL 90.4879 mL
5 mM 0.7239 mL 3.6195 mL 7.2390 mL 18.0976 mL
10 mM 0.3620 mL 1.8098 mL 3.6195 mL 9.0488 mL
15 mM 0.2413 mL 1.2065 mL 2.4130 mL 6.0325 mL
20 mM 0.1810 mL 0.9049 mL 1.8098 mL 4.5244 mL
25 mM 0.1448 mL 0.7239 mL 1.4478 mL 3.6195 mL
30 mM 0.1207 mL 0.6033 mL 1.2065 mL 3.0163 mL
40 mM 0.0905 mL 0.4524 mL 0.9049 mL 2.2622 mL
50 mM 0.0724 mL 0.3620 mL 0.7239 mL 1.8098 mL
60 mM 0.0603 mL 0.3016 mL 0.6033 mL 1.5081 mL
80 mM 0.0452 mL 0.2262 mL 0.4524 mL 1.1311 mL
100 mM 0.0362 mL 0.1810 mL 0.3620 mL 0.9049 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lactucin1891-29-8莴苣素山莴苣素ApoptosisParasiteLeukemiaanti-inflammatoryantimalarial activityanticancerPlasmodium falciparumanalgesic activityInhibitorinhibitorinhibit

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