1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. MC-GGFG-DX8951

MC-GGFG-DX8951 

目录号: HY-114233
产品使用指南

MC-GGFG-DX8951是一种带有 MC-GGFG 连接桥的 DX8951。MC-GGFG-DX8951 可用于 DX8951 抗体偶联物 (ADC) 中,在 ADC 内化到肿瘤组织后,溶酶体酶可以将其裂解。

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MC-GGFG-DX8951 Chemical Structure

MC-GGFG-DX8951 Chemical Structure

CAS No. : 1600418-29-8

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Description

MC-GGFG-DX8951 is a DX8951 with MC-GGFG linker. MC-GGFG-DX8951 can be used to develop DX8951 antibody conjugate (ADC), which is cleaved by lysosomal enzymes following ADC internalization into tumor tissue[1].

Molecular Weight

946.97

Formula

C₄₉H₅₁FN₈O₁₁

CAS No.

1600418-29-8

SMILES

O=C1OCC2=C(C=C(C3=NC4=CC(F)=C(C)C(CC[C@@H]5NC(CNC([C@@H](NC(CNC(CNC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)=C4C5=C3C8)N8C2=O)[C@@]1(O)CC

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
MC-GGFG-DX8951
目录号:
HY-114233
需求量:

MC-GGFG-DX8951

Cat. No.: HY-114233