1. Metabolic Enzyme/Protease
  2. Epoxide Hydrolase
  3. mEH-IN-1

mEH-IN-1 (Compound 62) 是一种有效的微粒体环氧化物水解酶 (mEH) 抑制剂,IC50 为 2.2 nM。mEH 是哺乳动物的 α/β-折叠水解酶,在几乎所有组织中都有表达,可水解多种含环氧化物的分子。mEH 主要位于真核细胞的内质网 (ER)。mEH-IN-1 可用于先兆子痫、高胆碱血症和癌症的研究。

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mEH-IN-1 Chemical Structure

mEH-IN-1 Chemical Structure

CAS No. : 2418576-06-2

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  • 生物活性

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生物活性

mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1].

分子量

385.37

Formula

C16H17F6NOS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
mEH-IN-1
目录号:
HY-146696
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