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MK771 是促甲状腺激素释放激素类似物。MK771 诱导眨眼和前爪舔。MK771具有研究吗啡戒断综合征的潜力。

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MK771 Chemical Structure

MK771 Chemical Structure

CAS No. : 66537-55-1

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MK771 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MK771 is a thyrotrophin-releasing hormone analog. MK771 induces blinking and forepaw licking. MK771 has the potential for the research of morphine abstinence syndrome[1][2].

体内研究
(In Vivo)

MK771 (5 mg/kg；腹腔注射) 诱导小鼠眨眼和前爪舔[1]。
MK771 (10 ng-10 µg/小鼠；i.c.v.) 在小鼠体内产生高热反应[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 20-30 g, male MF1 mice[1]
Dosage: 5 mg/kg
Administration: I.p.
Result: Induced blinking and forepaw licking in both acutely isolated and paired mice.
Animal Model: 20-30 g, male MF1 mice[1]
Dosage: 0.25-60 mg/kg
Administration: I.p.
Result: Induced blinking was bell-shaped with an ED50 value of 1.72 mg/kg.
Animal Model: 25-30 g, Male Swiss-Webster mice[2]
Dosage: 10 ng-10 µg/mouse
Administration: I.c.v.
Result: Produced a hyperthermic response for 4 h followed by a return to normal temperature.
分子量

394.45

Formula

C16H22N6O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MK771 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MK77166537-55-1MK 771MK-771Othersthyrotrophin-releasing hormoneblinkingforepaw lickinghyperthermicmorphine abstinence syndromeInhibitorinhibitorinhibit

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