2. Others Autophagy JAK/STAT Signaling Stem Cell/Wnt Epigenetics Apoptosis Protein Tyrosine Kinase/RTK
  3. JAK Autophagy Isotope-Labeled Compounds Apoptosis
  4. Momelotinib-d4 dihydrochloride hydrate

Momelotinib-d4 dihydrochloride hydrate  (Synonyms: CYT387-d4 hydrochloride hydrate)

目录号: HY-10961S8
产品使用指南 技术支持

Momelotinib-d4 (CYT387-d4) dihydrochloride hydrate 是氘代标记的 Momelotinib (HY-10961)。Momelotinib (CYT387) 是 ATP 竞争性的 JAK1/JAK2 抑制剂，IC50 值分别为 11 nM/18 nM，是对 JAK3 选择性的 10 倍左右。

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Momelotinib-d<sub>4</sub> dihydrochloride hydrate Chemical Structure

Momelotinib-d4 dihydrochloride hydrate Chemical Structure

CAS No. : 2056097-81-3

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Other Forms of Momelotinib-d4 dihydrochloride hydrate:

Momelotinib-d4 dihydrochloride hydrate 相关抗体

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JAK1 JAK2 JAK3 Tyk2 JAK

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Momelotinib-d4 (CYT387-d4) dihydrochloride hydrate is a deuterium labeled Momelotinib (HY-10961). Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50s of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3[1].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Momelotinib-d4 dihydrochloride hydrate 相关抗体:
分子量

509.42

Formula

C23H22D4Cl2N6O3
CAS 号
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Momelotinib-d4 dihydrochloride hydrate 相关分类

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Keywords:

Momelotinib-d4 dihydrochloride2056097-81-3CYT387-d4 hydrochlorideJAKAutophagyIsotope-Labeled CompoundsApoptosisJanus kinaseInhibitorinhibitorinhibit

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