1. Others
  2. Others
  3. NQO1 activator 1

NQO1 activator 1 

目录号: HY-128895
产品使用指南

NQO1 activator 1 是一种口服的 NAD+调节剂,与 NAD(P)H: 醌氧化还原酶 1 (NQO1) 作为底物反应,通过 NADH 氧化导致细胞内 NAD+ 水平增加。升高的 NAD+ 水平触发 SIRT1 和 AMPK 的激活,并随后激活 PGC-1α。NQO1 activator 1 改善线粒体脑肌病、乳酸酸中毒和中风样发作 (MELAS) 成纤维细胞的能量代谢和线粒体功能障碍。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

NQO1 activator 1 Chemical Structure

NQO1 activator 1 Chemical Structure

CAS No. : 1800405-30-4

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
1 mg   Get quote  
5 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. Elevated NAD+ levels triggers the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts[1].

IC50 & Target

NQO1[1]

Molecular Weight

240.26

Formula

C₁₄H₁₂N₂O₂

CAS No.

1800405-30-4

SMILES

O=C(C1=C2N=C(C(C)C)N1)C(C3=C2C=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
NQO1 activator 1
目录号:
HY-128895
需求量:

NQO1 activator 1

Cat. No.: HY-128895