1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Drug Metabolite
  3. O-Desmethyl Midostaurin-d5

O-Desmethyl Midostaurin-d5  (Synonyms: CGP62221-d5; O-Desmethyl PKC412-d5)

目录号: HY-129491S
产品使用指南

O-Desmethyl Midostaurin-d5 是 O-Desmethyl PKC412 的氘代物。O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) 是 Midostaurin (HY-10230) 的活性代谢物,通过细胞色素 P450 肝酶代谢产生,可以作为 Midostaurin 在体内代谢的指标之一。

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O-Desmethyl Midostaurin-d<sub>5</sub> Chemical Structure

O-Desmethyl Midostaurin-d5 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

O-Desmethyl Midostaurin-d5 is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism[1].

IC50 & Target

IC50: active metabolite of Midostaurin[1]

分子量

561.64

Formula

C34H23D5N4O4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
O-Desmethyl Midostaurin-d5
目录号:
HY-129491S
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