1. Vitamin D Related/Nuclear Receptor
  2. Thyroid Hormone Receptor
  3. Osteostatin (human)

Osteostatin (human)  (Synonyms: Human PTHrP(107-139))

目录号: HY-P4800
产品使用指南

Osteostatin (human) 是甲状旁腺激素相关蛋白(PTHrP) 107-139片段,促进骨缺损动物模型中的骨修复,防止炎症性关节炎中的骨侵蚀。

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Custom Peptide Synthesis

Osteostatin (human) Chemical Structure

Osteostatin (human) Chemical Structure

CAS No. : 137348-10-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Osteostatin (human), a fragment of parathyroid hormone-related protein (PTHrP) 107-139, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis[1].

体外研究
(In Vitro)

Osteostatin (100, 250 and 500 nM) 剂量依赖性的降低破骨细胞的分化,但不改变成熟破骨细胞的吸收能力。此外,Osteostatin 可降低组织蛋白酶K、破骨细胞相关IG样受体(OSCAR)和NFATc1的mRNA水平[1]
Osteostatin可增强含Zn2+离子的介孔玻璃支架在人间充质干细胞培养中的生物活性[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3451.58

Formula

C142H228N42O58

CAS 号
Sequence

Thr-Arg-Ser-Ala-Trp-Leu-Asp-Ser-Gly-Val-Thr-Gly-Ser-Gly-Leu-Glu-Gly-Asp-His-Leu-Ser-Asp-Thr-Ser-Thr-Thr-Ser-Leu-Glu-Leu-Asp-Ser-Arg

Sequence Shortening

TRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Osteostatin (human)
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