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  3. Pyridaben-d13

Pyridaben-d13  (Synonyms: 哒螨灵-d13)

目录号: HY-B0817S
产品使用指南

Pyridaben-d13 是 Pyridaben 的氘代物。 Pyridaben 是一种线粒体电子传递抑制剂 (METI) 杀螨剂,会促进破坏性的氧和氮自由基的形成。Pyridaben 可选择性抑制 复合物 I (NADH 脱氢酶),其 IC50 值为 2.4 nM (检测位点:大鼠肝脏和牛心的线粒体)。Pyridaben 还能显著阻碍大鼠线粒体 mtNOS 功能。

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Pyridaben-d<sub>13</sub> Chemical Structure

Pyridaben-d13 Chemical Structure

CAS No. : 2468638-05-1

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规格 价格 是否有货 数量
1 mg ¥2678
3 - 4 周
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  • 生物活性

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生物活性

Pyridaben-d13 is the deuterium labeled Pyridaben[1]. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

378.01

Formula

C19H12D13ClN2OS

CAS 号
中文名称

哒螨灵-d13

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Pyridaben-d13 相关分类

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