Animal-Free MIF 蛋白, Mouse (His)

The MIF protein is a pro-inflammatory cytokine that plays a crucial role in the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests its role as a mediator in the regulation of macrophage function during host defense. Animal-Free MIF Protein, Mouse (His) is the recombinant mouse-derived animal-FreeMIF protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free MIF Protein, Mouse (His) is 115 a.a., with molecular weight of ~13.31 kDa.

MIF 蛋白是一种促炎细胞因子，在针对细菌病原体的先天免疫反应中发挥着至关重要的作用。它在炎症部位的表达表明它在宿主防御过程中作为调节巨噬细胞功能的介质。值得注意的是，MIF 可以对抗糖皮质激素的抗炎活性。虽然它在体外表现出苯丙酮酸互变异构酶和多巴色素互变异构酶活性，但其生理底物仍然未知。其互变异构酶活性的重要性及其与细胞因子功能的相关性仍不清楚。

Mouse

E. coli

C-His

P34884 (M1-A115)

17319  [NCBI]

MPMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSKLLCGLLSDRLHISPDRVYINYYDMNAANVGWNGSTFA

Approximately 13.31 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 7.4.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.