1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Peptide Hormone & Neuropeptides
  4. Calcitonin
  5. Calcitonin/CALCA 蛋白, Mouse (HEK293, Fc)

Calcitonin/CALCA 蛋白, Mouse (HEK293, Fc)

目录号: HY-P77587
COA 产品使用指南

降钙素/CALCA 蛋白诱导不同血管的血管舒张,包括冠状动脉、脑血管和全身血管。它高度集中在中枢神经系统中,表明其具有神经递质或神经调节剂的作用。此外,它还会增加血小板 cAMP 水平,可能影响血小板功能。Calcitonin/CALCA 蛋白, Mouse (HEK293, Fc) 是重组的 降钙素/CALCA 蛋白,由 HEK293 表达,带有 C-hFc 标签。Calcitonin/CALCA 蛋白, Mouse (HEK293, Fc) 全长 94 个氨基酸,分子量为 42-46 kDa。

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规格 价格 是否有货 数量
10 μg ¥1200 In-stock
50 μg ¥3360 In-stock
100 μg   询价  

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描述

The Calcitonin/CALCA protein induces vasodilation in different blood vessels, including the coronary, cerebral, and systemic vasculature. It is highly concentrated in the central nervous system, suggesting a role as a neurotransmitter or neuromodulator. Moreover, it increases platelet cAMP levels, possibly affecting platelet function. Calcitonin/CALCA Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Calcitonin/CALCA protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Calcitonin/CALCA Protein, Mouse (HEK293, Fc) is 94 a.a., with molecular weight of 42-46 kDa.

研究背景

降钙素/CALCA 蛋白已知可诱导血管舒张,影响各种类型的血管,如冠状动脉、脑血管和全身血管。它在中枢神经系统中的高浓度表明它作为神经递质或神经调节剂参与。此外,还观察到它会增加血小板环磷酸腺苷 (cAMP) 水平,表明其对血小板功能的潜在影响。

种属

Mouse

表达系统

HEK293

标签

C-hFc

蛋白编号

Q99JA0 (V26-D119)

基因 ID

12310  [NCBI]

蛋白结构
N-term
CALCA (V26-D119)
Accession # Q99JA0
hFc
C-term
同用名
Calcitonin; CCP; PDN-21; CALCA; CALC1; CGRP; CGRP-I; CGRP1; CT; KC; PCT; Procalcitonin; Calcitonin 1; Katacalcin
分子量

42-46 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before

内毒素含量

<0.1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

Calcitonin/CALCA Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Calcitonin/CALCA Protein, Mouse (HEK293, Fc)
目录号:
HY-P77587
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