1. 重组蛋白
  2. Cytokines and Growth Factors Immune Checkpoint Proteins CD Antigens
  3. TNF Superfamily Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins NK Cell CD Proteins Macrophage CD Proteins Stem Cell CD Proteins
  4. TNF Receptor Superfamily CD27
  5. CD27/TNFRSF7 蛋白, Mouse (HEK293, His-Fc)

CD27/TNFRSF7 蛋白, Mouse (HEK293, His-Fc)

目录号: HY-P72743
COA 产品使用指南

CD27/NFRSF7 蛋白作为 CD70/CD27L 的受体,支持激活的 T 细胞存活,并可能通过与 SIVA1 相互作用影响细胞凋亡。它形成同二聚体并与 SIVA1 和 TRAF2 结合,表明在细胞过程中发挥不同的作用。CD27/TNFRSF7 蛋白, Mouse (HEK293, His-Fc) 是重组的 CD27/TNFRSF7 蛋白,由 HEK293 表达,带有 C-hFc, C-6*His 标签。CD27/TNFRSF7 蛋白, Mouse (HEK293, His-Fc) 全长 159 个氨基酸,分子量为 60-66 kDa。

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重组蛋白定制服务

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
10 μg ¥750 In-stock
50 μg ¥2350 In-stock
100 μg   询价  

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描述

CD27/NFRSF7 Protein acts as a receptor for CD70/CD27L, supporting activated T-cell survival and potentially influencing apoptosis through interactions with SIVA1. It forms homodimers and engages with SIVA1 and TRAF2, indicating diverse roles in cellular processes. CD27/TNFRSF7 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived CD27/TNFRSF7 protein, expressed by HEK293 , with C-hFc, C-6*His labeled tag. The total length of CD27/TNFRSF7 Protein, Mouse (HEK293, His-Fc) is 159 a.a., with molecular weight of 60-66 kDa.

研究背景

CD27/NFRSF7 蛋白作为 CD70/CD27L 的受体,与活化 T 细胞的存活有关。此外,它可能通过与 SIVA1 相互作用在细胞凋亡中发挥作用。该蛋白形成同二聚体并与 SIVA1 和 TRAF2 结合,表明它参与多种细胞过程。

种属

Mouse

表达系统

HEK293

标签

C-hFc;C-6*His

蛋白编号

P41272 (P24-R182)

基因 ID

21940  [NCBI]

蛋白结构
N-term
CD27 (P24-R182)
Accession # P41272
hFc-6*His
C-term
同用名
CD27 antigen; CD27; T-cell activation antigen CD27; T14; TNFRSF7
氨基酸序列

PNSCPDKHYWTGGGLCCRMCEPGTFFVKDCEQDRTAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECSCSKNWQCRDQECTECDPPLNPALTRQPSETPSPQPPPTHLPHGTEKPSWPLHRQLPNSTVYSQRSSHRPLCSSDCIR

分子量

60-66 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD27/TNFRSF7 Protein, Mouse (HEK293, His-Fc)
目录号:
HY-P72743
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