CSF1R 蛋白, Human (430a.a, sf9, His-GST)

CSF1R protein is ubiquitously found in mononuclear phagocytes, especially macrophages and monocytes, and is involved in a variety of biological processes. It induces the release of proinflammatory chemokines in response to IL34 and CSF1, contributing to innate immunity and inflammation. CSF1R Protein, Human (430a.a, sf9, His-GST) is the recombinant human-derived CSF1R protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of CSF1R Protein, Human (430a.a, sf9, His-GST) is 430 a.a., with molecular weight of ~75 kDa.

CSF1R 蛋白尤其存在于巨噬细胞和单核细胞等单核吞噬细胞中，参与多种生物过程。它响应 IL34 和 CSF1 促进促炎趋化因子的释放，有助于先天免疫和炎症过程。此外，CSF1R 对于调节破骨细胞增殖和分化、骨吸收、正常骨骼和牙齿发育至关重要。它也是男性和女性正常生育能力以及怀孕期间乳腺中乳管和腺泡结构发育所必需的。

Human

Sf9 insect cells

N-His;N-GST

P07333 (K543-C972)

1436  [NCBI]

Approximately 75 kDa

Greater than 82% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, pH 7.4, 20% glycerol, 0.3 mM DTT.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.