Dxr/DXP reductoisomerase 蛋白, E.coli (Myc, His)

Dxr/DXP Reductoisomerase is pivotal in isoprenoid biosynthesis, catalyzing the rearrangement and reduction of DXP to yield MEP. This step is critical in forming isoprenoid precursors, essential for cellular processes and metabolite synthesis. The enzyme's activity emphasizes its significance in regulating isoprenoid biosynthesis and cellular functions. Dxr/DXP reductoisomerase Protein, E.coli (Myc, His) is the recombinant E. coli-derived Dxr/DXP reductoisomerase protein, expressed by E. coli , with C-Myc, N-10*His labeled tag. The total length of Dxr/DXP reductoisomerase Protein, E.coli (Myc, His) is 398 a.a., with molecular weight of ~48.4 kDa.

Dxr/DXP 还原异构酶是一种在类异戊二烯生物合成中发挥关键作用的蛋白质。它催化 NADPH 依赖性重排和 1-脱氧-D-木酮糖-5-磷酸 (DXP)（非甲羟戊酸途径中的关键中间体）的还原，产生 2-C-甲基-D-赤藓糖醇 4-磷酸（环境保护部）。这种酶促转化代表类异戊二烯前体形成的关键步骤，类异戊二烯前体是参与各种细胞过程（包括必需代谢物和信号分子的合成）的必需化合物。Dxr/DXP 还原异构酶的活性强调了其在类异戊二烯生物合成和细胞功能调节中的重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

E.coli

E. coli

C-Myc;N-10*His

P45568 (1M-398S)

66671539  [NCBI]

MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVEQCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIVGAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSLPQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKISVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKEVMRLAS

Approximately 48.4 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized after extensive dialysis against solution in 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.