Gamma-GCS 蛋白, E.coli (His-SUMO)

Gamma-GCS protein is a key enzyme in sulfur metabolism and initiates glutathione synthesis by catalyzing the incorporation of L-cysteine and L-glutamic acid. This important molecule critical for cellular antioxidant defense is synthesized through a critical 1/2 step facilitated by γ-GCS. Gamma-GCS Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Gamma-GCS protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of Gamma-GCS Protein, E.coli (His-SUMO) is 518 a.a., with molecular weight of ~74.3 kDa.

Gamma-GCS 蛋白是硫代谢和谷胱甘肽生物合成中的关键酶，促进 L-半胱氨酸和 L-谷氨酸形成谷胱甘肽的关键步骤 1/2。作为酶促过程的一部分，γ-GCS 催化 L-半胱氨酸和 L-谷氨酸的结合，引发谷胱甘肽的合成。这种分子对于细胞抗氧化防御和解毒至关重要，在维持细胞内氧化还原稳态方面发挥着至关重要的作用。通过协调谷胱甘肽生物合成的初始步骤，γ-GCS 有助于防止氧化应激和支持整体细胞健康的细胞机制。

E.coli

E. coli

N-His;N-SUMO

P0A6W9 (1M-518A)

944881  [NCBI]

MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA

Approximately 74.3 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.