GAMT 蛋白, Human (His)

GAMT protein uses S-adenosylmethionine as a methyl donor to catalyze the conversion of guanidinoacetic acid into creatine, playing a key role in cell metabolism. This enzyme activity is essential for the biosynthesis of creatine, a compound necessary for cellular energy storage and transport. GAMT Protein, Human (His) is the recombinant human-derived GAMT protein, expressed by E. coli , with N-6*His, C-6*His labeled tag. The total length of GAMT Protein, Human (His) is 236 a.a., with molecular weight of 27-32 kDa.

GAMT 蛋白是一种重要的酶，利用 S-腺苷甲硫氨酸作为甲基供体，将胍基乙酸转化为肌酸。这种生化过程对于肌酸生物合成至关重要，肌酸是参与能量代谢的关键化合物，特别是在肌肉和大脑等能量需求较高的组织中。GAMT 的酶活性在神经系统发育中特别重要，强调了其在确保肌酸的可用性以实现正常细胞功能方面的重要性。GAMT 将胍基乙酸转化为肌酸是维持肌酸水平平衡、有助于能量稳态和支持正常神经发育的关键步骤。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-6*His;C-6*His

Q14353 (M1-G236)

2593  [NCBI]

MSAPSATPIFAPGENCSPAWGAAPAAYDAADTHLRILGKPVMERWETPYMHALAAAASSKGGRVLEVGFGMAIAASKVQEAPIDEHWIIECNDGVFQRLRDWAPRQTHKVIPLKGLWEDVAPTLPDGHFDGILYDTYPLSEETWHTHQFNFIKNHAFRLLKPGGVLTYCNLTSWGELMKSKYSDITIMFEETQVPALLEAGFRRENIRTEVMALVPPADCRYYAFPQMITPLVTKG

27-32 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 1 mM DTT, pH 8.0 .

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.