1. 重组蛋白
  2. Biotinylated Proteins
  3. HLA-G Complex Tetramer 蛋白, Cynomolgus (HEK293, His-Avi)

HLA-G Complex Tetramer 蛋白, Cynomolgus (HEK293, His-Avi)

目录号: HY-P77687
产品使用指南

HLA-A*0201 WT-1 复合蛋白是 MHC I 类家族的成员,对于免疫功能至关重要,可将抗原肽呈递给细胞毒性 T 淋巴细胞。该蛋白与 HLA-A*0201 等位基因相关,有助于免疫监视和防御机制。在抗原呈递中,HLA-A*0201 WT-1 复合蛋白有助于识别和消除异常或受感染的细胞,强调其在维持免疫稳态中的重要性。HLA-G Complex Tetramer 蛋白, Cynomolgus (HEK293, His-Avi) 是重组的蛋白二聚体复合物,包含 HLA-G 和 B2M/Beta-2 microglobulin Protein,由 HEK293 表达,带有 C-Avi, C-His 标签,和 RIIPRHLQL 肽。HLA-G Complex Tetramer 蛋白, Cynomolgus (HEK293, His-Avi),分子量为 260-265 kDa。

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描述

HLA-A*0201 WT-1 Complex Protein, a member of the MHC class I family, is crucial for immune function, presenting antigenic peptides to cytotoxic T lymphocytes. Associated with the HLA-A*0201 allele, this protein contributes to immune surveillance and defense mechanisms. In antigen presentation, HLA-A*0201 WT-1 Complex Protein aids in recognizing and eliminating abnormal or infected cells, emphasizing its significance in maintaining immune homeostasis. HLA-G Complex Tetramer Protein, Cynomolgus (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G and B2M/Beta-2 microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. HLA-G Complex Tetramer Protein, Cynomolgus (HEK293, His-Avi), has molecular weight of 260-265 kDa.

研究背景

HLA-A*0201 WT-1 复合蛋白是 MHC I 类家族的成员,通过向细胞毒性 T 淋巴细胞呈递抗原肽,在免疫功能中发挥着至关重要的作用。该蛋白的特点是与 HLA-A*0201 等位基因相关,有助于免疫系统的监视和防御机制。通过参与抗原呈递,HLA-A*0201 WT-1 复合蛋白有助于识别和消除异常或受感染的细胞,凸显其在维持免疫稳态方面的重要性。

种属

Cynomolgus

表达系统

HEK293

标签

C-Avi;C-His

蛋白编号

E0WKX9 (G25-T305)&Q8SPW0 (I21-M119)&RIIPRHLQL

基因 ID

102117143&101867173  [NCBI]

同用名
HLA G antigen; sHLA-G; b2 microglobulin; HLA G; HLAG; HLA-G; MHC Class I Antigen G; MHC class Ib antigen; MHC-G; sHLA-G
分子量

260-265 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

HLA-G Complex Tetramer Protein, Cynomolgus (HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
HLA-G Complex Tetramer Protein, Cynomolgus (HEK293, His-Avi)
目录号:
HY-P77687
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