1. 重组蛋白
  2. Fc Receptors
  3. Immunoglobulin Fc Region
  4. IgG3
  5. IgG3 Fc 蛋白, Mouse (HEK293)

IgG3 Fc 蛋白, Mouse (HEK293)

目录号: HY-P70251
产品使用指南

IgG3 Fc 蛋白是 IgG3 (免疫球蛋白 G3) 的高度保守 Fc 片段。小鼠 IgG3 Fc 蛋白参与多个过程,例如免疫反应激活、B 细胞信号传导、补体激活。IgG3 Fc 蛋白, Mouse (HEK293) 是重组的 IgG3 Fc 蛋白,由 HEK293 表达,不带标签。IgG3 Fc 蛋白, Mouse (HEK293) 全长 210 个氨基酸,分子量约为 ~31.0 kDa。

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1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

IgG3 Fc Protein is the high conserved Fc segment of IgG3 (Immunoglobulin G3). Mouse IgG3 Fc protein is involved in several processes, such as activation of immune response, B-cell signaling, complement activation[1][2]. IgG3 Fc Protein, Mouse (HEK293) is the recombinant mouse-derived IgG3 Fc protein, expressed by HEK293 , with tag free. The total length of IgG3 Fc Protein, Mouse (HEK293) is 210 a.a., with molecular weight of ~31.0 kDa.

研究背景

IgG 由四个亚类组成: IgG1、IgG2、IgG3 和 IgG4。在四个亚类中,IgG3 对每种人 Fcγ 受体 (FcγRI、FcγRIIA/B/C、FcγRIIIA/B) 均具有较高的亲和力,并且具有较高的补体激活能力[1]IgG3 Fc 蛋白是 IgG3 (免疫球蛋白 G3) 的高度保守的 Fc 片段。人 IgG3 Fc 蛋白与小鼠 IgG3 Fc 蛋白氨基酸序列同源性仅具有约 68%。

种属

Mouse

表达系统

HEK293

标签

Tag Free

蛋白编号

P03987-2 (E97-T306)

基因 ID

380795

蛋白结构
N-term
IgG3 Fc (E97-T306)
Accession # P03987-2
C-term
同用名
rMuIg gamma-3 chain C region/IgG3 Fc; Ig gamma-3 chain C region,IgG3 Fc
氨基酸序列

EPRIPKPSTPPGSSCPPGNILGGPSVFIFPPKPKDALMISLTPKVTCVVVDVSEDDPDVHVSWFVDNKEVHTAWTQPREAQYNSTFRVVSALPIQHQDWMRGKEFKCKVNNKALPAPIERTISKPKGRAQTPQVYTIPPPREQMSKKKVSLTCLVTNFFSEAISVEWERNGELEQDYKNTPPILDSDGTYFLYSKLTVDTDSWLQGEIFTCSVVHEALHNHHTQKNLSRSPGK

分子量

Approximately 31.0 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

IgG3 Fc Protein, Mouse (HEK293) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
IgG3 Fc Protein, Mouse (HEK293)
目录号:
HY-P70251
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