1. 重组蛋白
  2. Cytokines and Growth Factors Receptor Proteins Biotinylated Proteins
  3. Interleukin & Receptors Cytokine Receptors
  4. IL-13 Receptor
  5. IL-13R alpha 2 蛋白, Human (Biotinylated, HEK293, His)

IL-13R alpha 2 蛋白, Human (Biotinylated, HEK293, His)

目录号: HY-P75829
产品使用指南

IL-13R α 2 蛋白作为单体发挥作用,仅与白细胞介素 13 (IL13) 表现出高亲和力结合,而不与白细胞介素 4 (IL4) 相互作用。这种结合选择性表明 IL-13R α2 在介导细胞对 IL13 的反应中具有独特的作用和特异性,强调了其在 IL13 相关细胞过程中的重要性。IL-13R alpha 2 蛋白, Human (Biotinylated, HEK293, His) 是重组的 IL-13R α 2 蛋白,由 HEK293 表达,带有 C-His 标签。IL-13R alpha 2 蛋白, Human (Biotinylated, HEK293, His) 全长 316 个氨基酸,分子量约为 ~38 kDa。

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描述

IL-13R alpha 2 Protein, functioning as a monomer, exhibits high-affinity binding exclusively to interleukin-13 (IL13) without interaction with interleukin-4 (IL4). This binding selectivity indicates a unique role and specificity for IL-13R alpha 2 in mediating cellular responses to IL13, emphasizing its importance in IL13-associated cellular processes. IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His) is 316 a.a., with molecular weight of ~38 kDa.

研究背景

IL-13R α2 蛋白作为具有高亲和力的单体发挥作用,特异性结合白细胞介素 13 (IL13),但不结合白细胞介素 4 (IL4)。这种结合选择性表明 IL-13R α2 在介导 IL13 反应中具有独特的作用和特异性,突出了其在与该细胞因子相关的细胞过程中的重要性。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

Q14627/NP_000631.1 (D27-L342)

基因 ID
蛋白结构
N-term
IL-13Rα2 (M1-L342)
Accession # Q14627
His
C-term
同用名
Interleukin-13 receptor subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13RA2; IL13R
分子量

Approximately 38 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His)
目录号:
HY-P75829
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