1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-2
  5. IL-2 蛋白, Human

IL-2 蛋白, Human

目录号: HY-P7037
COA 产品使用指南

IL-2 蛋白, Human 来源于E. coli,可用作治疗结核病 (TB) 的辅助免疫治疗剂。

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规格 价格 是否有货 数量
10 μg ¥900 In-stock
50 μg ¥2200 In-stock
100 μg   询价  
250 μg   询价  

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  • 生物活性

  • 技术参数

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  • 产品资料

  • 参考文献

描述

IL-2 Protein, Human is an adjunctive immunotherapeutic agent to treat tuberculosis (TB).

研究背景

Recombinant human interleukin-2 (IL-2) expressed as Escherichia coli is isolated as insoluble aggregates of protein (inclusion bodies) after cell breakage. Interleukin 2 (IL-2), a cytokine secreted by activated T cells, promotes the differentiation and proliferation of lymphoid cells as well as enhances the cell-mediated immune response to infections. Therefore IL-2 has been used as an adjunctive immunotherapeutic agent to control some infectious diseases, such as leishmaniasis, leprosy, and HIV infection[1].

生物活性

The ED50 is <0.1 ng/mL as measured by CTLL-2 cells, corresponding to a specific activity of >1 × 107 units/mg.

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

P60568 (A21-T153)

基因 ID
同用名
rHuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin
氨基酸序列

MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT

分子量

Approximately 14 kDa

性状

Lyophilized powder.

组分

Lyophilized after extensive dialysis against 50mM Phosphate buffer, pH7.5, 5% Mannitol buffer.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
参考文献

IL-2 Protein, Human 相关分类

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific active calculator equation

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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