Ketohexokinase/KHK 蛋白, Human (HEK293, His)

Ketohexokinase (KHK) proteins play a key role in carbohydrate metabolism by catalyzing the phosphorylation of ketoglycosides into fructose-1-phosphate. This enzyme activity is a key step in the utilization and processing of fructose within cells. Ketohexokinase/KHK Protein, Human (HEK293, His) is the recombinant human-derived Ketohexokinase/KHK protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Ketohexokinase/KHK Protein, Human (HEK293, His) is 298 a.a., with molecular weight of ~30.0 kDa.

酮己糖激酶 (KHK) 蛋白是一种重要的酶，可催化酮糖果糖的磷酸化，将其转化为 1-磷酸果糖。这种磷酸化反应代表果糖代谢的关键步骤，对于调节各种细胞过程至关重要。通过启动果糖向 1-磷酸果糖的转化，KHK 在将果糖从糖酵解转向其他代谢途径方面发挥着核心作用。这种酶在肝脏中特别重要，它有助于调节果糖代谢及其对脂肪生成和甘油三酯合成的潜在影响。了解 KHK 的功能有助于深入了解控制果糖利用的分子机制及其对代谢稳态的影响。参考资料：所提供的信息基于截至 2022 年 1 月的一般知识，未引用具体参考资料。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-6*His

AAH06233.1 (M1-V298)

3795  [NCBI]

MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV

Approximately 30.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 50nM KCl, 10% Glycerol, pH 7.4.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.