S100A11 蛋白, Mouse (His)

The S100A11 protein plays a crucial role in promoting keratinocyte differentiation and keratinization, suggesting its involvement in important processes related to skin development and integrity. As a disulfide-linked homodimer, S100A11 may contribute to the molecular machinery that regulates keratinocyte maturation and specialized functions. S100A11 Protein, Mouse (His) is the recombinant mouse-derived S100A11 protein, expressed by E. coli , with N-6*His labeled tag. The total length of S100A11 Protein, Mouse (His) is 98 a.a., with molecular weight of ~12.0 kDa.

S100A11 蛋白，也称为 S100C 或 calgizzarin，在角质形成细胞的分化和角化过程中起着至关重要的作用，角质形成细胞是皮肤外层的主要细胞。它作为同二聚体发挥作用，这意味着它形成由两个相同的亚基组成的复合物。二聚化通过二硫键发生，其中两个硫原子形成一个键，有助于蛋白质的稳定性和结构。S100A11 蛋白参与角质形成细胞分化和角化，表明其在维持皮肤完整性和屏障功能方面具有重要意义。

Mouse

E. coli

N-6*His

P50543 (M1-I98)

20195  [NCBI]

MPTETERCIESLIAVFQKYSGKDGNNTQLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNCDGQLDFQEFLNLIGGLAIACHDSFIQTSQKRI

Approximately 12.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.