SDC4 蛋白, Mouse (HEK293, His)

SDC4 protein is a cell surface proteoglycan that cooperates with SDCBP and PDCD6IP to regulate exosome biogenesis. SDC4 exists as a homodimer and engages in important interactions with various intracellular partners. SDC4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SDC4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SDC4 Protein, Mouse (HEK293, His) is 122 a.a., with molecular weight of ~22.21 kDa.

Syndecan-4 (SDC4) 是一种细胞表面蛋白聚糖，与 SDCBP 和 PDCD6IP 合作，在调节外泌体生物发生中发挥着至关重要的作用。作为同二聚体，SDC4 参与各种蛋白质相互作用，包括与 CDCP1 和 SDCBP 结合，表明它参与多种细胞过程。通过其胞质结构域，SDC4 与 GIPC（特别是通过 PDZ 结构域）以及 NUDT16L1 形成相互作用。这些关联凸显了 SDC4 的多功能性质，表明它参与复杂的细胞信号传导途径和外泌体动力学的调节。

Mouse

HEK293

C-6*His

O35988 (E24-E145)

20971  [NCBI]

ESIRETEVIDPQDLLEGRYFSGALPDDEDAGGSDDFELSGSGDLDDTEEPRPFPEVIEPLVPLDNHIPENAQPGIRVPSEPKELEENEVIPKRAPSDVGDDMSNKVSMSSTAQGSNIFERTE

Approximately 22.21 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.