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  2. 化合物库
  3. 生物活性化合物库系列
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  5. 抗体偶联药物毒素分子库
抗体偶联药物毒素分子库 - Toxins for Antibody-Drug Conjugate Research Library

Cat. No.: HY-L023

抗体偶联药物 (ADCs) 是由单克隆抗体、连接剂和细胞毒素组成的一类新型癌症治疗药物。到目前为止,已经有多种 ADC 药物通过批准上市,60 多种 ADC 药物处于临床研究阶段。抗体偶联药物是全球增长最快的抗肿瘤药物之一。

细胞毒素是抗体偶联药物的重要组成部分。抗体偶联药物对肿瘤细胞的毒性主要来自于毒素分子。MCE 可以提供 90 种有效的毒素分子,包括 auristatin 衍生物,maytansinoids,calicheamicin,duocarmycin,pyrrolobenzodiazepines (PBDs) 等。

  • 96-well Plate with Peelable Foil Seal
- +

Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料

活性描述 & 特点

Biological Activity

•   A unique collection of 90 ADC cytotoxins for targeted therapy research.

•   Used to develop new antibody-drug conjugates targeting cancer.

•   Bioactivity and safety confirmed by preclinical research and clinical trials.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 90 ADC cytotoxins supplied as solid powder

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96-well Storage Tubes with Rack

Storage:

-80°C

Shipping:

Blue ice

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  • 96-well Plate with Peelable Foil Seal

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    产品名称:
    Toxins for Antibody-Drug Conjugate Research Library
    目录号:
    HY-L023
    需求量: