1. Metabolic Enzyme/Protease Stem Cell/Wnt Anti-infection
  2. LDLR Wnt CMV
  3. SGC-CK1γ-1

SGC-CK1γ-1 是一种高效且具有选择性的 CK1γ 亚家族探针。SGC-CK1γ-1 能够抑制 LRP6 的磷酸化水平。SGC-CK1γ-1 可以选择性地抑制活细胞中的 CK1γ 激酶,并同时抑制 WNT 信号传导以及人类巨细胞病毒 (CMV) 的复制。SGC-CK1γ-1 可用于感染方面的研究。

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SGC-CK1γ-1

SGC-CK1γ-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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查看 Wnt 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SGC-CK1γ-1 is a potent and selective probe for the CK1γ subfamily. SGC-CK1γ-1 can inhibit LRP6 phosphorylation levels. SGC-CK1γ-1 can selectively inhibit the CK1γ kinases in living cells and inhibit both WNT signaling and human cytomegalovirus (CMV) replication. SGC-CK1γ-1 can be used for the research of infection[1].

体外研究
(In Vitro)

SGC-CK1γ-1 (5-10 μM, 2h) 可抑制 HEK293 细胞中 LRP6 的磷酸化水平[1]
SGC-CK1γ-1 (10 μM, 24-48 h) 对 HEK293 细胞的活力没有影响[1]
SGC-CK1γ-1 (1-10 μM) 在 HFF 细胞中具有抗人巨细胞病毒 (HCMV) 复制的作用[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

353.81

Formula

C18H16ClN5O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SGC-CK1γ-1
目录号:
HY-178335
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