2. Membrane Transporter/Ion Channel Metabolic Enzyme/Protease
  3. Xanthine Oxidase URAT1
  4. URAT1&XO inhibitor 2

URAT1&XO inhibitor 2 

目录号: HY-153972 纯度: 98.69%
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摩尔计算器

URAT1&XO inhibitor 2 (Compound BDEO) 是黄嘌呤氧化酶 (xanthine oxidase) 和 URAT1 的双重抑制剂，对黄嘌呤氧化酶的 IC50 为3.3 μM。URAT1&XO inhibitor 2 阻断表达URAT1的HEK293细胞对尿酸的摄取，Ki 值为0.145 μM。URAT1&XO inhibitor 2 降低高尿酸血症小鼠的血清尿酸盐水平和尿酸排泄。URAT1&XO inhibitor 2 用于高尿酸血症研究。

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URAT1&XO inhibitor 2 Chemical Structure

URAT1&XO inhibitor 2 Chemical Structure

CAS No. : 1239488-96-0

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规格 价格 是否有货 数量
5 mg ￥1000
In-stock
10 mg ￥1600
In-stock
25 mg ￥3200
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50 mg ￥5100
In-stock
100 mg ￥7800
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URAT1&XO inhibitor 2 相关抗体

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生物活性

URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a Ki value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia[1].

分子量

322.15

Formula

C14H12BrNO3
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

URAT1&XO inhibitor 2 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

URAT1&XO inhibitor 21239488-96-0Xanthine OxidaseURAT1XOUrate transporter 1SLC22A12hyperuricemiauric acid excretionHEK293serum urateInhibitorinhibitorinhibit

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