1. GPCR/G Protein
  2. LPL Receptor
  3. VPC 23019

VPC 23019 

目录号: HY-108490
产品使用指南

VPC23019,一种含芳基酰胺的鞘氨醇 1-磷酸 (S1P) receptor 调节剂,S1P1S1P3 受体的竞争性拮抗剂 (pKis=7.86 和 5.93),S1P4S1P5 的激动剂 (pEC50s=6.58 和 7.07)。

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VPC 23019 Chemical Structure

VPC 23019 Chemical Structure

CAS No. : 449173-19-7

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Description

VPC23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKis = 7.86 and 5.93, respectively) and a agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively)[1].

IC50 & Target

pKi: 7.86 (S1P1); 5.93 (S1P3)[1]

Molecular Weight

372.40

Formula

C₁₇H₂₉N₂O₅P

CAS No.

449173-19-7

SMILES

O=C(NC1=CC=CC(CCCCCCCC)=C1)[C@H](N)COP(O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
VPC 23019
目录号:
HY-108490
需求量:

VPC 23019

Cat. No.: HY-108490